node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG31935 | Gdi | FBpp0077582 | FBpp0311558 | Rab3 GTPase-activating protein catalytic subunit; Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3 subfamily. Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Specifically converts active Rab3-GTP to the inactive form Rab3-GDP (By similarity). | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | 0.483 |
CG31935 | Rab3-GAP | FBpp0077582 | FBpp0079885 | Rab3 GTPase-activating protein catalytic subunit; Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3 subfamily. Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Specifically converts active Rab3-GTP to the inactive form Rab3-GDP (By similarity). | Rab3 GTPase-activating protein regulatory subunit; Probable regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily. Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab3 GTPase- activating complex specifically converts active Rab3-GTP to the inactive form Rab3-GDP (By similarity). | 0.999 |
CG31935 | Rab3-GEF | FBpp0077582 | FBpp0303427 | Rab3 GTPase-activating protein catalytic subunit; Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3 subfamily. Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Specifically converts active Rab3-GTP to the inactive form Rab3-GDP (By similarity). | MAP kinase-activating death domain protein; Plays significant role in regulating cell proliferation, survival and death through alternative mRNA splicing. Plays an important regulatory role in physiological cell death, caspase-mediated apoptosis (By similarity). Converts GDP-bound inactive form of Rab3 to the GTP-bound active forms. | 0.525 |
CG31935 | Rbcn-3A | FBpp0077582 | FBpp0292404 | Rab3 GTPase-activating protein catalytic subunit; Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3 subfamily. Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Specifically converts active Rab3-GTP to the inactive form Rab3-GDP (By similarity). | Rabconnectin-3A (Rbcn-3A) encodes a protein that is part of a regulatory subunit of the Vacuolar H[+] ATPase required for acidification of intracellular vesicles and the lysosome. It is involved in endocytic trafficking and lysosome function, and mutations block Notch signaling in follicle cells and imaginal disc cells. | 0.481 |
Dyb | Rab3-GEF | FBpp0111987 | FBpp0303427 | Dystrobrevin, isoform F; Zinc ion binding; structural constituent of muscle. It is involved in the biological process described with: synaptic signaling. | MAP kinase-activating death domain protein; Plays significant role in regulating cell proliferation, survival and death through alternative mRNA splicing. Plays an important regulatory role in physiological cell death, caspase-mediated apoptosis (By similarity). Converts GDP-bound inactive form of Rab3 to the GTP-bound active forms. | 0.492 |
Gdi | CG31935 | FBpp0311558 | FBpp0077582 | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | Rab3 GTPase-activating protein catalytic subunit; Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3 subfamily. Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Specifically converts active Rab3-GTP to the inactive form Rab3-GDP (By similarity). | 0.483 |
Gdi | Rab27 | FBpp0311558 | FBpp0070280 | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | EG:80H7.4 protein; Rab27 (Rab27) encodes a Rab GTPase involved in exosomal secretion. | 0.844 |
Gdi | Rab3 | FBpp0311558 | FBpp0087352 | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | Ras-related protein Rab-3; Rab3 (Rab3) encodes a member of a large family of Ras-like small GTPases. Localized primarily at the synapse, Rab3 product is involved in mechanisms that control synaptic development and function, including the regulation of active zone protein composition at the neuromuscular junction. | 0.913 |
Gdi | Rab3-GAP | FBpp0311558 | FBpp0079885 | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | Rab3 GTPase-activating protein regulatory subunit; Probable regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily. Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab3 GTPase- activating complex specifically converts active Rab3-GTP to the inactive form Rab3-GDP (By similarity). | 0.714 |
Gdi | Rab3-GEF | FBpp0311558 | FBpp0303427 | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | MAP kinase-activating death domain protein; Plays significant role in regulating cell proliferation, survival and death through alternative mRNA splicing. Plays an important regulatory role in physiological cell death, caspase-mediated apoptosis (By similarity). Converts GDP-bound inactive form of Rab3 to the GTP-bound active forms. | 0.640 |
Gdi | Rab35 | FBpp0311558 | FBpp0305729 | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | Rab35, isoform A; Rab35 (Rab35) encodes a protein that regulates proximal versus distal growth of seamless tubes in the terminal cells of the tracheal system. | 0.925 |
Rab27 | Gdi | FBpp0070280 | FBpp0311558 | EG:80H7.4 protein; Rab27 (Rab27) encodes a Rab GTPase involved in exosomal secretion. | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | 0.844 |
Rab27 | Rab3 | FBpp0070280 | FBpp0087352 | EG:80H7.4 protein; Rab27 (Rab27) encodes a Rab GTPase involved in exosomal secretion. | Ras-related protein Rab-3; Rab3 (Rab3) encodes a member of a large family of Ras-like small GTPases. Localized primarily at the synapse, Rab3 product is involved in mechanisms that control synaptic development and function, including the regulation of active zone protein composition at the neuromuscular junction. | 0.510 |
Rab27 | Rab3-GEF | FBpp0070280 | FBpp0303427 | EG:80H7.4 protein; Rab27 (Rab27) encodes a Rab GTPase involved in exosomal secretion. | MAP kinase-activating death domain protein; Plays significant role in regulating cell proliferation, survival and death through alternative mRNA splicing. Plays an important regulatory role in physiological cell death, caspase-mediated apoptosis (By similarity). Converts GDP-bound inactive form of Rab3 to the GTP-bound active forms. | 0.790 |
Rab27 | Rab35 | FBpp0070280 | FBpp0305729 | EG:80H7.4 protein; Rab27 (Rab27) encodes a Rab GTPase involved in exosomal secretion. | Rab35, isoform A; Rab35 (Rab35) encodes a protein that regulates proximal versus distal growth of seamless tubes in the terminal cells of the tracheal system. | 0.588 |
Rab3 | Gdi | FBpp0087352 | FBpp0311558 | Ras-related protein Rab-3; Rab3 (Rab3) encodes a member of a large family of Ras-like small GTPases. Localized primarily at the synapse, Rab3 product is involved in mechanisms that control synaptic development and function, including the regulation of active zone protein composition at the neuromuscular junction. | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | 0.913 |
Rab3 | Rab27 | FBpp0087352 | FBpp0070280 | Ras-related protein Rab-3; Rab3 (Rab3) encodes a member of a large family of Ras-like small GTPases. Localized primarily at the synapse, Rab3 product is involved in mechanisms that control synaptic development and function, including the regulation of active zone protein composition at the neuromuscular junction. | EG:80H7.4 protein; Rab27 (Rab27) encodes a Rab GTPase involved in exosomal secretion. | 0.510 |
Rab3 | Rab3-GAP | FBpp0087352 | FBpp0079885 | Ras-related protein Rab-3; Rab3 (Rab3) encodes a member of a large family of Ras-like small GTPases. Localized primarily at the synapse, Rab3 product is involved in mechanisms that control synaptic development and function, including the regulation of active zone protein composition at the neuromuscular junction. | Rab3 GTPase-activating protein regulatory subunit; Probable regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily. Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab3 GTPase- activating complex specifically converts active Rab3-GTP to the inactive form Rab3-GDP (By similarity). | 0.753 |
Rab3 | Rab3-GEF | FBpp0087352 | FBpp0303427 | Ras-related protein Rab-3; Rab3 (Rab3) encodes a member of a large family of Ras-like small GTPases. Localized primarily at the synapse, Rab3 product is involved in mechanisms that control synaptic development and function, including the regulation of active zone protein composition at the neuromuscular junction. | MAP kinase-activating death domain protein; Plays significant role in regulating cell proliferation, survival and death through alternative mRNA splicing. Plays an important regulatory role in physiological cell death, caspase-mediated apoptosis (By similarity). Converts GDP-bound inactive form of Rab3 to the GTP-bound active forms. | 0.928 |
Rab3 | Rab35 | FBpp0087352 | FBpp0305729 | Ras-related protein Rab-3; Rab3 (Rab3) encodes a member of a large family of Ras-like small GTPases. Localized primarily at the synapse, Rab3 product is involved in mechanisms that control synaptic development and function, including the regulation of active zone protein composition at the neuromuscular junction. | Rab35, isoform A; Rab35 (Rab35) encodes a protein that regulates proximal versus distal growth of seamless tubes in the terminal cells of the tracheal system. | 0.794 |