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STRINGSTRING
Pdp protein (fruit fly) - STRING interaction network
"Pdp" - Protein serine/threonine phosphatase activity in Drosophila melanogaster
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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PdpProtein serine/threonine phosphatase activity; [pyruvate dehydrogenase (lipoamide)] phosphatase activity; phosphoprotein phosphatase activity. It is involved in the biological process described with- protein dephosphorylation; pyruvate metabolic process (475 aa)    
Predicted Functional Partners:
l(1)G0334
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (443 aa)
     
  0.986
CG7024
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (479 aa)
     
  0.977
CG11876
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2 (365 aa)
     
  0.973
CG5261
Midline uncoordinated, isoform B; Dihydrolipoyllysine-residue acetyltransferase activity. It is involved in the biological process described with- acetyl-CoA biosynthetic process from pyruvate (512 aa)
     
  0.971
CG3626
FI22513p1; [pyruvate dehydrogenase (lipoamide)] phosphatase regulator activity; oxidoreductase activity. It is involved in the biological process described with- oxidation-reduction process (939 aa)
   
  0.970
CG7430
Dihydrolipoyl dehydrogenase activity; flavin adenine dinucleotide binding. It is involved in the biological process described with- tricarboxylic acid cycle; lipoamide metabolic process; cell redox homeostasis; glycine catabolic process (504 aa)
     
  0.970
Pdk
[Pyruvate dehydrogenase (acetyl-transferring)] kinase, mitochondrial; Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism; Belongs to the PDK/BCKDK protein kinase family (422 aa)
     
 
  0.934
PpV
Serine/threonine-protein phosphatase 6 catalytic subunit; May be involved in controlling cellularization or in regulating transcription of the genes involved in this process (303 aa)
     
 
  0.712
Aats-cys
Cysteine--tRNA ligase, cytoplasmic; tRNA binding; ATP binding; cysteine-tRNA ligase activity. It is involved in the biological process described with- cysteinyl-tRNA aminoacylation (741 aa)
     
 
  0.697
Dd
CTD nuclear envelope phosphatase 1 homolog; Serine/threonine protein phosphatase that may dephosphorylate and activate lipin-like phosphatases. Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol (By similarity) (243 aa)
     
 
  0.635
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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