STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
salaProtein spalt-accessory; Likely to be involved in the establishment of the head. (142 aa)    
Predicted Functional Partners:
Ilp4
Insulin-like peptide 4 (Ilp4) encodes a protein involved in larval feeding behavior; Belongs to the insulin family.
   
    0.967
link
LD15563p.
   
    0.846
CG8960
GEO04221p1.
   
    0.843
CG4440
GEO09613p1.
   
    0.843
Brd
Bearded (Brd) encodes a member of the Bearded family, which are small proteins containing predicted basic amphipathic alpha-helical domains in their N-terminal regions. The product of Brd is involved in Notch signaling pathway regulation and cell fate specification.
   
    0.842
Tom
Twin of m4 (Tom) is a member of the Bearded gene family that encodes a regulator of the Notch signaling pathway.
   
    0.841
CG10035
Uncharacterized protein, isoform A.
   
    0.841
Inx3
Innexin 3 (Inx3) encodes a gap junction protein that can form heteromeric gap junction channels via interaction with the product of Inx2. Loss of Inx3 leads to the destabilization of the products of ogre, Inx2 and shg at the plasma membrane, suggesting that these four proteins form a complex.
   
    0.623
CG10479
Uncharacterized protein, isoform B.
   
    0.620
halo
Halo (halo) encodes a protein that acts as cofactor of the molecular motor kinesin-1 and controls travel distances of moving lipid droplets. It determines the intracellular distribution of lipid droplets.
   
    0.614
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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