STRINGSTRING
CanB2 protein (fruit fly) - STRING interaction network
"CanB2" - Calcineurin B2 in Drosophila melanogaster
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CanB2Calcineurin B2; Calcineurin is a calcium-binding and calmodulin-binding protein found in all cells from yeast to mammals, and a calcium- dependent, calmodulin-stimulated protein phosphatase (170 aa)    
Predicted Functional Partners:
Pp2B-14D
Protein binding; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin (570 aa)
     
  0.990
CanA1
Calcineurin A1; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin (622 aa)
     
  0.989
CanB
Calcineurin B; Calcineurin is a calcium-binding and calmodulin-binding protein found in all cells from yeast to mammals, and a calcium- dependent, calmodulin-stimulated protein phosphatase (170 aa)
     
0.983
CanA-14F
Calcineurin A at 14F; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin (584 aa)
     
  0.977
Pp4-19C
Protein phosphatase 19C; Protein phosphatase that regulates many processes such as microtubule organization at centrosomes. The probable PP4 complex Pp4-19C-PPP4R2r-flfl (PPP4C-PPP4R2-PPP4R3) is required to prevent caspase-induced cell death (in vitro) (307 aa)
     
  0.936
Nos
Nitric oxide synthase; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. Truncated isoforms (isoform 3-isoform 6) are able to form intracellular complexes with the full length protein and serve as dominant negative inhibitors of the enzyme activity (1349 aa)
       
 
  0.931
Mbs
Myosin binding subunit (1273 aa)
     
  0.914
tws
Twins; Could perform a substrate recognition function or could be responsible for targeting the enzyme complex to the appropriate subcellular compartment (499 aa)
     
 
  0.913
Pp2A-29B
Protein phosphatase 2A at 29B; The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit (650 aa)
     
 
    0.904
sra
Sarah; Required for elongation of meiosis I spindle. Critical for ovulation, meiotic progression in oocytes and female courtship behavior, including their postmating changes. Regulates female meiosis by controlling calcineurin activity in the germline. Has a role in calcium signaling during egg activation; bcd mRNA polyadenylation and translation in the oocyte (292 aa)
       
 
  0.904
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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