STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Myo10AMyosin 10A (Myo10A) encodes an unconventional myosin of the MyTH-FERM superclass that traffics sensory, cytoskeletal, and adhesion cargos. It is required during dorsal closure for proper epithelial alignment and for zippering and fusion of the two epithelial sheets; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (3145 aa)    
Predicted Functional Partners:
CG18135
Uncharacterized protein, isoform D; Starch binding; glycerophosphocholine phosphodiesterase activity; myosin binding. It is involved in the biological process described with: glycerophospholipid catabolic process; multicellular organism reproduction.
    
 
 0.762
elgi
Early girl (elgi) encodes a myosin binding protein involved in the regulation of meiosis and Fat signaling pathway.
    
 
 0.698
Sans
Scaffold protein containing ankyrin repeats and SAM domain (Sans) encodes a putative scaffolding protein containing three ankyrin repeats and a sterile alpha motif domain.
   
 
 0.652
dysc
Dyschronic, isoform G; Dyschronic (dysc) encodes a protein that regulates the localization of the calcium-activated potassium channel encoded by slo. The product of dysc impacts circadian locomotor patterns, synaptic morphology, active zone structure, and both spontaneous and evoked neurotransmitter release.
    
 
 0.618
CG5921
Uncharacterized protein, isoform D; Actin filament binding; spectrin binding. It is involved in the biological process described with: sensory perception of sound; G2/M transition of mitotic cell cycle.
   
 
 0.511
fra
Frazzled, isoform A; Frazzled (fra) encodes a DCC-like Netrin receptor that mediates axon guidance. It also contributes to dendrite guidance, development and morphogenesis.
   
   0.501
CG30056
Uncharacterized protein.
    
   0.497
CG2852
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
      
 0.495
CG10433
RE36793p; It is involved in the biological process described with: regulation of female receptivity; multicellular organism reproduction; defense response.
      
 0.450
Bbd
Uncharacterized protein, isoform A; It is involved in the biological process described with: multicellular organism reproduction.
      
 0.435
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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