STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
alpha-Est2Alpha-Esterase-2, isoform A; Carboxylic ester hydrolase activity. (566 aa)    
Predicted Functional Partners:
CG1288
FI08143p.
      
 0.680
CG14609
AT27838p.
      
 0.680
DZIP1
Uncharacterized protein, isoform A; Nucleic acid binding. It is involved in the biological process described with: cilium assembly.
      
 0.670
CG11893
IP11926p.
   
  
 0.665
CG44014
Uncharacterized protein.
      
 0.627
CG7900
Amidase domain-containing protein; Anandamide amidohydrolase activity; acylglycerol lipase activity.
   
  
 0.619
CG9084
Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family.
   
  
 0.555
Lsp1beta
Larval serum protein 1 beta chain; Larval storage protein (LSP) which may serve as a store of amino acids for synthesis of adult proteins; Belongs to the hemocyanin family.
   
  
 0.535
CG12780
CG12780 protein; Carbohydrate binding. It is involved in the biological process described with: defense response to virus; detection of biotic stimulus.
   
  
 0.532
CG8562
FI02848p; Metallocarboxypeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis.
   
  
 0.522
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.