STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACXEAdenylyl cyclase X E; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1123 aa)    
Predicted Functional Partners:
CG17202
c-Myc-binding protein homolog; Transcription coactivator activity. It is involved in the biological process described with: regulation of transcription, DNA-templated.
      
 0.791
Nepl7
Neprilysin-like 7, isoform A; Metalloendopeptidase activity. It is involved in the biological process described with: proteolysis.
      
 0.669
RpL7-like
Ribosomal protein L7-like, isoform A; Structural constituent of ribosome; RNA binding. It is involved in the biological process described with: maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); cytoplasmic translation.
    
 
 0.629
CG31705
BcDNA.GH07269.
      
 0.627
CG17572
RH69521p; It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
      
 0.610
ppk14
Pickpocket 14; Sodium channel activity. It is involved in the biological process described with: sodium ion transport; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
      
 0.606
NimB1
Nimrod B1, isoform B; It is involved in the biological process described with: defense response to bacterium.
      
 0.602
Vha68-3
Vacuolar H[+] ATPase 68kD subunit 3; ATP binding; proton-transporting ATPase activity, rotational mechanism. It is involved in the biological process described with: proton transmembrane transport; ATP metabolic process.
      
 0.497
Sidpn
Similar to deadpan; Protein dimerization activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of neurogenesis; anterior/posterior pattern specification; negative regulation of transcription by RNA polymerase II; cell differentiation; regulation of transcription, DNA-templated.
      
 0.493
CG15483
Uncharacterized protein; Glucuronosyltransferase activity. It is involved in the biological process described with: protein O-linked mannosylation.
   
  
 0.482
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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