Serine/threonine-protein kinase Tor; Promotes cell and tissue growth, maintains tissue homeostatis and controls responses to environmental stress and aging. Regulates growth during animal development by coupling growth factor signaling to nutrient availability. Central regulators of autophagy. May be involved in atg1 phosphorylation. May also be involved, directly or indirectly, in the control of neuronal function. Phosphorylates S6K/p70S6K, in vitro. May regulate the activity of S6K. Overexpression inhibits growth and reduces cell size. Affects the timing of neuronal cell differentiat [...]

Rasputin, isoform B; Rasputin (rin) encodes an RNA-binding protein that regulates gene expression. It is involved in eye development and the dorsal/ventral axis specification of the ovary.

Synaptic functional regulator FMR1; Polyribosome-associated RNA-binding protein that plays a role in neuronal development and synaptic plasticity through the regulation of protein synthesis of mRNAs. Plays a role as a negative translational regulator of specific mRNAs. Represses translation of the microtubule-associated protein futsch mRNA to regulate microtubule-dependent synaptic growth and function. May also be involved in microRNA (miRNA)-mediated translational suppression as part of the RNA-induced silencing complex (RISC). Required for stability of the central pair of microtubule [...]

Caprin (Capr) encodes an RNA-binding translational regulator that is present in cytoplasmic RNA granules (neuronal granules and stress granules). It modulates diverse cellular processes including neuronal function, cell proliferation and differentiation through post-transcriptional regulation of target RNAs.

GH09295p; Metal ion binding; endopeptidase activity; metalloendopeptidase activity. It is involved in the biological process described with: protein processing involved in protein targeting to mitochondrion; protein processing.

FI13301p; Oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process; mitochondrial respiratory chain complex I assembly.

Protein-arginine omega-N asymmetric methyltransferase activity; protein-arginine omega-N monomethyltransferase activity; histone methyltransferase activity (H4-R3 specific); histone methyltransferase activity. It is involved in the biological process described with: histone methylation; histone H4-R3 methylation; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.

No circadian temperature entrainment (nocte) encodes a protein involved in temperature compensation of the circadian clock.

Translational regulator orb2; Required in mushroom body gamma neurons for long-term memory in male courtship. Binds to mRNA 3'- UTRs. In its monomeric form, acts as a translational repressor of genes involved in neuronal growth, synapse formation and protein turnover. In its amyloid- like oligomeric form, acts as a translational activator. The monomeric form reduces poly(A) tail length and destabilizes mRNA while the oligomeric form protects and elongates the poly(A) tail and stabilizes mRNA. Isoform A is required for initial memory acquisition and, following subsequent late dopaminerg [...]