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CG3708 protein (fruit fly) - STRING interaction network
CG3708 in Drosophila melanogaster
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG3708CG3708; Histone binding. It is involved in the biological process described with- nucleosome assembly (362 aa)    
Predicted Functional Partners:
FBXO11
F-box protein 11 is a subunit of a SCF-like E3 ubiquitin ligase. It is involved in gene silencing mediated by both siRNAs and miRNAs (1182 aa)
       
      0.809
Set
Protein SET; Cyclin binding. It is involved in the biological process described with- nucleosome assembly (269 aa)
     
 
  0.793
bip2
Bip2; P53 binding; protein binding; zinc ion binding; POZ domain binding; transcription factor binding; chromatin binding. It is involved in the biological process described with- positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter (1406 aa)
       
      0.724
His2Av
Histone H2A.v; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Acts as a Polycomb group (PcG) protein required to maintain the transcriptionally repres [...] (141 aa)
     
 
  0.702
Ranbp9
Ran GTPase binding. It is involved in the biological process described with- intracellular protein transport (1018 aa)
     
 
  0.686
Hrd3
annotation not available (819 aa)
       
 
  0.682
Mys45A
Protein SDA1 homolog; Required for 60S pre-ribosomal subunits export to the cytoplasm (712 aa)
     
 
  0.670
RpS6
40S ribosomal protein S6; May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA (248 aa)
     
 
  0.652
snRNP-U1-C
U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5’ splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5’ splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5’ splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5’ end of the U1 snRNA and the 5’ splice-site region (By similarity). Regulat [...] (145 aa)
     
 
  0.616
cerv
Cervantes, isoform A; SUMO ligase activity. It is involved in the biological process described with- DNA repair; double-strand break repair via homologous recombination (230 aa)
     
      0.609
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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