node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Elys | Nup107 | FBpp0074515 | FBpp0079710 | Protein ELYS homolog; Component of the nuclear pore complex. Binds to transcriptionally active chromatin including regulatory regions. | Nuclear pore complex protein Nup107; Plays a role in nuclear pore complex (NPC) assembly and maintenance. Required for nuclear import of Mad. Plays a role in double strand break repair by relocalizing the heterochromatic double strain breaks (DSBs) to the nuclear periphery as part of the homologous recombination (HR) repair process. Regulates cytokinesis during spermatocyte meiosis by maintaining type-B lamin Lam localization to the spindle envelope. Regulates female gonad development and oogenesis. Belongs to the nucleoporin Nup84/Nup107 family. | 0.999 |
Elys | Nup133 | FBpp0074515 | FBpp0083695 | Protein ELYS homolog; Component of the nuclear pore complex. Binds to transcriptionally active chromatin including regulatory regions. | Nuclear pore complex protein Nup133; Probable component of the nuclear pore complex (NPC) (Probable). Plays a role in NPC assembly and/or maintenance. | 0.998 |
Elys | Nup160 | FBpp0074515 | FBpp0079788 | Protein ELYS homolog; Component of the nuclear pore complex. Binds to transcriptionally active chromatin including regulatory regions. | Nuclear pore complex protein Nup160 homolog; Functions as a component of the nuclear pore complex (NPC). Involved in poly(A)+ RNA transport (By similarity). Required for nuclear import of Mad. May play a role in double strand break DNA repair. Essential for nephrocyte development. | 0.997 |
Elys | Nup35 | FBpp0074515 | FBpp0074372 | Protein ELYS homolog; Component of the nuclear pore complex. Binds to transcriptionally active chromatin including regulatory regions. | Nucleoporin Nup35; Functions as a component of the nuclear pore complex (NPC) (By similarity). May have a role in the organization of the inner nuclear membrane proteins at the nuclear envelope together with Nup154. | 0.985 |
Elys | Nup37 | FBpp0074515 | FBpp0304467 | Protein ELYS homolog; Component of the nuclear pore complex. Binds to transcriptionally active chromatin including regulatory regions. | Nucleoporin Nup37; As part of the nuclear pore complex (NPC), has a role in its assembly and function. | 0.997 |
Elys | Nup43 | FBpp0074515 | FBpp0082998 | Protein ELYS homolog; Component of the nuclear pore complex. Binds to transcriptionally active chromatin including regulatory regions. | Nucleoporin 43kD; It is involved in the biological process described with: mitotic cell cycle. | 0.996 |
Elys | Nup44A | FBpp0074515 | FBpp0087937 | Protein ELYS homolog; Component of the nuclear pore complex. Binds to transcriptionally active chromatin including regulatory regions. | Nucleoporin seh1; Probable component of the nuclear pore complex (NPC) (By similarity). Involved in maintaining the localization of another nucleoporin Mtor to the nuclear envelope of early meiotic female germline cells. It is not involved in recruiting the nucleoporins Mtor, Nup107, Nup153 and FG-containing nucleoporins to the NPC ; Belongs to the WD repeat SEC13 family. | 0.996 |
Elys | Nup75 | FBpp0074515 | FBpp0085954 | Protein ELYS homolog; Component of the nuclear pore complex. Binds to transcriptionally active chromatin including regulatory regions. | Nuclear pore complex protein Nup75; Component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance (By similarity). Required for nuclear import of phosphorylated Mad via importin msk. Has no role in classical nuclear localization signal (cNLS)-dependent nuclear import via importin-beta. Facilitates the interaction between Nup93 and sec13 with msk. | 0.991 |
Elys | Nup98-96 | FBpp0074515 | FBpp0083851 | Protein ELYS homolog; Component of the nuclear pore complex. Binds to transcriptionally active chromatin including regulatory regions. | Nuclear pore complex protein Nup98-Nup96; Part of the nuclear pore complex (NPC). Required for MAD import as part of the Nup107-160 complex and required for nuclear export of Moe probably via its association with Rae1. Plays a role in nuclear mRNA export. Promotes cell antiviral response by upregulating FoxK-dependent antiviral gene transcription. In germline stem cells, involved in their maintenance and division together with the TGF-Beta and EGFR signaling pathways. In larval lymph glands, has a role in the maintenance of hematopoiesis by regulating Pvr expression. [Nuclear pore comp [...] | 0.995 |
Elys | Sec13 | FBpp0074515 | FBpp0311988 | Protein ELYS homolog; Component of the nuclear pore complex. Binds to transcriptionally active chromatin including regulatory regions. | Protein SEC13 homolog; Functions as a component of the nuclear pore complex (NPC) and the COPII coat (By similarity). At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles (By similarity). Recruited to transcriptionally active chromatin at the time of transcription initiation by RNA polymerase II. Required for proper expression of ecdysone-responsive genes such as Eip74EF and Eip75B during larval development. Required for reactivation of transcription after heat shock. Required for nuclear import of phosphorylated Mad via importin msk. Has no role i [...] | 0.995 |
Nup107 | Elys | FBpp0079710 | FBpp0074515 | Nuclear pore complex protein Nup107; Plays a role in nuclear pore complex (NPC) assembly and maintenance. Required for nuclear import of Mad. Plays a role in double strand break repair by relocalizing the heterochromatic double strain breaks (DSBs) to the nuclear periphery as part of the homologous recombination (HR) repair process. Regulates cytokinesis during spermatocyte meiosis by maintaining type-B lamin Lam localization to the spindle envelope. Regulates female gonad development and oogenesis. Belongs to the nucleoporin Nup84/Nup107 family. | Protein ELYS homolog; Component of the nuclear pore complex. Binds to transcriptionally active chromatin including regulatory regions. | 0.999 |
Nup107 | Nup133 | FBpp0079710 | FBpp0083695 | Nuclear pore complex protein Nup107; Plays a role in nuclear pore complex (NPC) assembly and maintenance. Required for nuclear import of Mad. Plays a role in double strand break repair by relocalizing the heterochromatic double strain breaks (DSBs) to the nuclear periphery as part of the homologous recombination (HR) repair process. Regulates cytokinesis during spermatocyte meiosis by maintaining type-B lamin Lam localization to the spindle envelope. Regulates female gonad development and oogenesis. Belongs to the nucleoporin Nup84/Nup107 family. | Nuclear pore complex protein Nup133; Probable component of the nuclear pore complex (NPC) (Probable). Plays a role in NPC assembly and/or maintenance. | 0.999 |
Nup107 | Nup160 | FBpp0079710 | FBpp0079788 | Nuclear pore complex protein Nup107; Plays a role in nuclear pore complex (NPC) assembly and maintenance. Required for nuclear import of Mad. Plays a role in double strand break repair by relocalizing the heterochromatic double strain breaks (DSBs) to the nuclear periphery as part of the homologous recombination (HR) repair process. Regulates cytokinesis during spermatocyte meiosis by maintaining type-B lamin Lam localization to the spindle envelope. Regulates female gonad development and oogenesis. Belongs to the nucleoporin Nup84/Nup107 family. | Nuclear pore complex protein Nup160 homolog; Functions as a component of the nuclear pore complex (NPC). Involved in poly(A)+ RNA transport (By similarity). Required for nuclear import of Mad. May play a role in double strand break DNA repair. Essential for nephrocyte development. | 0.999 |
Nup107 | Nup35 | FBpp0079710 | FBpp0074372 | Nuclear pore complex protein Nup107; Plays a role in nuclear pore complex (NPC) assembly and maintenance. Required for nuclear import of Mad. Plays a role in double strand break repair by relocalizing the heterochromatic double strain breaks (DSBs) to the nuclear periphery as part of the homologous recombination (HR) repair process. Regulates cytokinesis during spermatocyte meiosis by maintaining type-B lamin Lam localization to the spindle envelope. Regulates female gonad development and oogenesis. Belongs to the nucleoporin Nup84/Nup107 family. | Nucleoporin Nup35; Functions as a component of the nuclear pore complex (NPC) (By similarity). May have a role in the organization of the inner nuclear membrane proteins at the nuclear envelope together with Nup154. | 0.997 |
Nup107 | Nup37 | FBpp0079710 | FBpp0304467 | Nuclear pore complex protein Nup107; Plays a role in nuclear pore complex (NPC) assembly and maintenance. Required for nuclear import of Mad. Plays a role in double strand break repair by relocalizing the heterochromatic double strain breaks (DSBs) to the nuclear periphery as part of the homologous recombination (HR) repair process. Regulates cytokinesis during spermatocyte meiosis by maintaining type-B lamin Lam localization to the spindle envelope. Regulates female gonad development and oogenesis. Belongs to the nucleoporin Nup84/Nup107 family. | Nucleoporin Nup37; As part of the nuclear pore complex (NPC), has a role in its assembly and function. | 0.999 |
Nup107 | Nup43 | FBpp0079710 | FBpp0082998 | Nuclear pore complex protein Nup107; Plays a role in nuclear pore complex (NPC) assembly and maintenance. Required for nuclear import of Mad. Plays a role in double strand break repair by relocalizing the heterochromatic double strain breaks (DSBs) to the nuclear periphery as part of the homologous recombination (HR) repair process. Regulates cytokinesis during spermatocyte meiosis by maintaining type-B lamin Lam localization to the spindle envelope. Regulates female gonad development and oogenesis. Belongs to the nucleoporin Nup84/Nup107 family. | Nucleoporin 43kD; It is involved in the biological process described with: mitotic cell cycle. | 0.999 |
Nup107 | Nup44A | FBpp0079710 | FBpp0087937 | Nuclear pore complex protein Nup107; Plays a role in nuclear pore complex (NPC) assembly and maintenance. Required for nuclear import of Mad. Plays a role in double strand break repair by relocalizing the heterochromatic double strain breaks (DSBs) to the nuclear periphery as part of the homologous recombination (HR) repair process. Regulates cytokinesis during spermatocyte meiosis by maintaining type-B lamin Lam localization to the spindle envelope. Regulates female gonad development and oogenesis. Belongs to the nucleoporin Nup84/Nup107 family. | Nucleoporin seh1; Probable component of the nuclear pore complex (NPC) (By similarity). Involved in maintaining the localization of another nucleoporin Mtor to the nuclear envelope of early meiotic female germline cells. It is not involved in recruiting the nucleoporins Mtor, Nup107, Nup153 and FG-containing nucleoporins to the NPC ; Belongs to the WD repeat SEC13 family. | 0.999 |
Nup107 | Nup75 | FBpp0079710 | FBpp0085954 | Nuclear pore complex protein Nup107; Plays a role in nuclear pore complex (NPC) assembly and maintenance. Required for nuclear import of Mad. Plays a role in double strand break repair by relocalizing the heterochromatic double strain breaks (DSBs) to the nuclear periphery as part of the homologous recombination (HR) repair process. Regulates cytokinesis during spermatocyte meiosis by maintaining type-B lamin Lam localization to the spindle envelope. Regulates female gonad development and oogenesis. Belongs to the nucleoporin Nup84/Nup107 family. | Nuclear pore complex protein Nup75; Component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance (By similarity). Required for nuclear import of phosphorylated Mad via importin msk. Has no role in classical nuclear localization signal (cNLS)-dependent nuclear import via importin-beta. Facilitates the interaction between Nup93 and sec13 with msk. | 0.999 |
Nup107 | Nup98-96 | FBpp0079710 | FBpp0083851 | Nuclear pore complex protein Nup107; Plays a role in nuclear pore complex (NPC) assembly and maintenance. Required for nuclear import of Mad. Plays a role in double strand break repair by relocalizing the heterochromatic double strain breaks (DSBs) to the nuclear periphery as part of the homologous recombination (HR) repair process. Regulates cytokinesis during spermatocyte meiosis by maintaining type-B lamin Lam localization to the spindle envelope. Regulates female gonad development and oogenesis. Belongs to the nucleoporin Nup84/Nup107 family. | Nuclear pore complex protein Nup98-Nup96; Part of the nuclear pore complex (NPC). Required for MAD import as part of the Nup107-160 complex and required for nuclear export of Moe probably via its association with Rae1. Plays a role in nuclear mRNA export. Promotes cell antiviral response by upregulating FoxK-dependent antiviral gene transcription. In germline stem cells, involved in their maintenance and division together with the TGF-Beta and EGFR signaling pathways. In larval lymph glands, has a role in the maintenance of hematopoiesis by regulating Pvr expression. [Nuclear pore comp [...] | 0.999 |
Nup107 | Sec13 | FBpp0079710 | FBpp0311988 | Nuclear pore complex protein Nup107; Plays a role in nuclear pore complex (NPC) assembly and maintenance. Required for nuclear import of Mad. Plays a role in double strand break repair by relocalizing the heterochromatic double strain breaks (DSBs) to the nuclear periphery as part of the homologous recombination (HR) repair process. Regulates cytokinesis during spermatocyte meiosis by maintaining type-B lamin Lam localization to the spindle envelope. Regulates female gonad development and oogenesis. Belongs to the nucleoporin Nup84/Nup107 family. | Protein SEC13 homolog; Functions as a component of the nuclear pore complex (NPC) and the COPII coat (By similarity). At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles (By similarity). Recruited to transcriptionally active chromatin at the time of transcription initiation by RNA polymerase II. Required for proper expression of ecdysone-responsive genes such as Eip74EF and Eip75B during larval development. Required for reactivation of transcription after heat shock. Required for nuclear import of phosphorylated Mad via importin msk. Has no role i [...] | 0.999 |