Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bub1 | BubR1 | FBpp0309714 | FBpp0085368 | Bub1 kinase (Bub1) encodes a spindle checkpoint protein regulating chromosome congression. It also contributes to clathrin-dependent endocytosis of pathogens. | Bub1-related kinase (BubR1) encodes a motif-rich protein with a C-terminal serine-threonine kinase domain. During prometaphase and metaphase, it plays important roles in spindle assembly checkpoint signalling, stabilization of kinetochore-microtuble attachments and chromosome alignment. It is also essential to maintain sister-chromatid cohesion during meiotic progression and for normal maintenance of Synaptonemal Complex in females. | 0.947 |
| Bub1 | Klp61F | FBpp0309714 | FBpp0072616 | Bub1 kinase (Bub1) encodes a spindle checkpoint protein regulating chromosome congression. It also contributes to clathrin-dependent endocytosis of pathogens. | Kinesin-like protein Klp61F; Important role in mitotic dividing cells. Microtubule motor required for spindle body separation. Slow plus-end directed microtubule motor capable of cross-linking and sliding apart antiparallel microtubules, thereby pushing apart the associated spindle poles during spindle assembly and function. Forms cross-links between microtubules within interpolar microtubule bundles. Contributes to the length of the metaphase spindle, maintains the prometaphase spindle by antagonizing Ncd, drives anaphase B, and also contributes to normal chromosome congression, kinet [...] | 0.804 |
| Bub1 | Klp67A | FBpp0309714 | FBpp0312148 | Bub1 kinase (Bub1) encodes a spindle checkpoint protein regulating chromosome congression. It also contributes to clathrin-dependent endocytosis of pathogens. | Kinesin-like protein at 67A (Klp67A) encodes a microtubule motor protein involved in chromosome congression and mitotic spindle morphogenesis; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.626 |
| Bub1 | Mps1 | FBpp0309714 | FBpp0303766 | Bub1 kinase (Bub1) encodes a spindle checkpoint protein regulating chromosome congression. It also contributes to clathrin-dependent endocytosis of pathogens. | Monopolar spindle 1, isoform B; Monopolar spindle 1 (Mps1) encodes a conserved protein kinase that is associated with kinetochores and is required for the mitotic and meiotic spindle assembly checkpoints. | 0.937 |
| Bub1 | Ndc80 | FBpp0309714 | FBpp0073681 | Bub1 kinase (Bub1) encodes a spindle checkpoint protein regulating chromosome congression. It also contributes to clathrin-dependent endocytosis of pathogens. | LD33040p; Ndc80 (Ndc80) encodes a protein involved in mitotic metaphase plate congression. | 0.986 |
| Bub1 | Zwilch | FBpp0309714 | FBpp0085138 | Bub1 kinase (Bub1) encodes a spindle checkpoint protein regulating chromosome congression. It also contributes to clathrin-dependent endocytosis of pathogens. | Protein zwilch; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin, Mad2 complexes and spindly/CG15415 onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the RZZ complex. Failure to assemble the complex due to the absence of any one of its components, results in the incorrect redistribution of the remaining components to diverse membrane compartments ; Belongs to the ZWILCH family. | 0.917 |
| Bub1 | asp | FBpp0309714 | FBpp0084071 | Bub1 kinase (Bub1) encodes a spindle checkpoint protein regulating chromosome congression. It also contributes to clathrin-dependent endocytosis of pathogens. | Protein abnormal spindle; Required to maintain the structure of the centrosomal microtubule organizing center (MTOC) during mitosis. May have a preferential role in regulating neurogenesis. Required for germ cell mitosis and oocyte differentiation. | 0.776 |
| Bub1 | aurB | FBpp0309714 | FBpp0079769 | Bub1 kinase (Bub1) encodes a spindle checkpoint protein regulating chromosome congression. It also contributes to clathrin-dependent endocytosis of pathogens. | Aurora B (aurB) encodes a serine-threonine kinase and member of the chromosomal passenger complex. It plays multiple roles in mitosis including the correction of erroneous chromosome-spindle interactions, chromosome condensation, kinetochore assembly, spindle assembly checkpoint and cytokinesis. | 0.820 |
| Bub1 | cmet | FBpp0309714 | FBpp0304511 | Bub1 kinase (Bub1) encodes a spindle checkpoint protein regulating chromosome congression. It also contributes to clathrin-dependent endocytosis of pathogens. | CENP-meta, isoform C; CENP-meta (cmet) encodes a kinetochore kinesin that contributes to metaphase chromosome alignment; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.940 |
| Bub1 | pav | FBpp0309714 | FBpp0073083 | Bub1 kinase (Bub1) encodes a spindle checkpoint protein regulating chromosome congression. It also contributes to clathrin-dependent endocytosis of pathogens. | Kinesin-like protein; Pavarotti (pav) encodes a microtubule motor protein from the Kinesin superfamily. It plays important roles during the mitotic cycle including spindle formation, cortical cytoskeleton reorganization and cytokinesis. It also negatively regulates Wnt activity. | 0.806 |
| BubR1 | Bub1 | FBpp0085368 | FBpp0309714 | Bub1-related kinase (BubR1) encodes a motif-rich protein with a C-terminal serine-threonine kinase domain. During prometaphase and metaphase, it plays important roles in spindle assembly checkpoint signalling, stabilization of kinetochore-microtuble attachments and chromosome alignment. It is also essential to maintain sister-chromatid cohesion during meiotic progression and for normal maintenance of Synaptonemal Complex in females. | Bub1 kinase (Bub1) encodes a spindle checkpoint protein regulating chromosome congression. It also contributes to clathrin-dependent endocytosis of pathogens. | 0.947 |
| BubR1 | Klp61F | FBpp0085368 | FBpp0072616 | Bub1-related kinase (BubR1) encodes a motif-rich protein with a C-terminal serine-threonine kinase domain. During prometaphase and metaphase, it plays important roles in spindle assembly checkpoint signalling, stabilization of kinetochore-microtuble attachments and chromosome alignment. It is also essential to maintain sister-chromatid cohesion during meiotic progression and for normal maintenance of Synaptonemal Complex in females. | Kinesin-like protein Klp61F; Important role in mitotic dividing cells. Microtubule motor required for spindle body separation. Slow plus-end directed microtubule motor capable of cross-linking and sliding apart antiparallel microtubules, thereby pushing apart the associated spindle poles during spindle assembly and function. Forms cross-links between microtubules within interpolar microtubule bundles. Contributes to the length of the metaphase spindle, maintains the prometaphase spindle by antagonizing Ncd, drives anaphase B, and also contributes to normal chromosome congression, kinet [...] | 0.905 |
| BubR1 | Klp67A | FBpp0085368 | FBpp0312148 | Bub1-related kinase (BubR1) encodes a motif-rich protein with a C-terminal serine-threonine kinase domain. During prometaphase and metaphase, it plays important roles in spindle assembly checkpoint signalling, stabilization of kinetochore-microtuble attachments and chromosome alignment. It is also essential to maintain sister-chromatid cohesion during meiotic progression and for normal maintenance of Synaptonemal Complex in females. | Kinesin-like protein at 67A (Klp67A) encodes a microtubule motor protein involved in chromosome congression and mitotic spindle morphogenesis; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.918 |
| BubR1 | Mps1 | FBpp0085368 | FBpp0303766 | Bub1-related kinase (BubR1) encodes a motif-rich protein with a C-terminal serine-threonine kinase domain. During prometaphase and metaphase, it plays important roles in spindle assembly checkpoint signalling, stabilization of kinetochore-microtuble attachments and chromosome alignment. It is also essential to maintain sister-chromatid cohesion during meiotic progression and for normal maintenance of Synaptonemal Complex in females. | Monopolar spindle 1, isoform B; Monopolar spindle 1 (Mps1) encodes a conserved protein kinase that is associated with kinetochores and is required for the mitotic and meiotic spindle assembly checkpoints. | 0.966 |
| BubR1 | Ndc80 | FBpp0085368 | FBpp0073681 | Bub1-related kinase (BubR1) encodes a motif-rich protein with a C-terminal serine-threonine kinase domain. During prometaphase and metaphase, it plays important roles in spindle assembly checkpoint signalling, stabilization of kinetochore-microtuble attachments and chromosome alignment. It is also essential to maintain sister-chromatid cohesion during meiotic progression and for normal maintenance of Synaptonemal Complex in females. | LD33040p; Ndc80 (Ndc80) encodes a protein involved in mitotic metaphase plate congression. | 0.992 |
| BubR1 | Zwilch | FBpp0085368 | FBpp0085138 | Bub1-related kinase (BubR1) encodes a motif-rich protein with a C-terminal serine-threonine kinase domain. During prometaphase and metaphase, it plays important roles in spindle assembly checkpoint signalling, stabilization of kinetochore-microtuble attachments and chromosome alignment. It is also essential to maintain sister-chromatid cohesion during meiotic progression and for normal maintenance of Synaptonemal Complex in females. | Protein zwilch; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin, Mad2 complexes and spindly/CG15415 onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the RZZ complex. Failure to assemble the complex due to the absence of any one of its components, results in the incorrect redistribution of the remaining components to diverse membrane compartments ; Belongs to the ZWILCH family. | 0.970 |
| BubR1 | asp | FBpp0085368 | FBpp0084071 | Bub1-related kinase (BubR1) encodes a motif-rich protein with a C-terminal serine-threonine kinase domain. During prometaphase and metaphase, it plays important roles in spindle assembly checkpoint signalling, stabilization of kinetochore-microtuble attachments and chromosome alignment. It is also essential to maintain sister-chromatid cohesion during meiotic progression and for normal maintenance of Synaptonemal Complex in females. | Protein abnormal spindle; Required to maintain the structure of the centrosomal microtubule organizing center (MTOC) during mitosis. May have a preferential role in regulating neurogenesis. Required for germ cell mitosis and oocyte differentiation. | 0.921 |
| BubR1 | aurB | FBpp0085368 | FBpp0079769 | Bub1-related kinase (BubR1) encodes a motif-rich protein with a C-terminal serine-threonine kinase domain. During prometaphase and metaphase, it plays important roles in spindle assembly checkpoint signalling, stabilization of kinetochore-microtuble attachments and chromosome alignment. It is also essential to maintain sister-chromatid cohesion during meiotic progression and for normal maintenance of Synaptonemal Complex in females. | Aurora B (aurB) encodes a serine-threonine kinase and member of the chromosomal passenger complex. It plays multiple roles in mitosis including the correction of erroneous chromosome-spindle interactions, chromosome condensation, kinetochore assembly, spindle assembly checkpoint and cytokinesis. | 0.976 |
| BubR1 | cmet | FBpp0085368 | FBpp0304511 | Bub1-related kinase (BubR1) encodes a motif-rich protein with a C-terminal serine-threonine kinase domain. During prometaphase and metaphase, it plays important roles in spindle assembly checkpoint signalling, stabilization of kinetochore-microtuble attachments and chromosome alignment. It is also essential to maintain sister-chromatid cohesion during meiotic progression and for normal maintenance of Synaptonemal Complex in females. | CENP-meta, isoform C; CENP-meta (cmet) encodes a kinetochore kinesin that contributes to metaphase chromosome alignment; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.990 |
| BubR1 | pav | FBpp0085368 | FBpp0073083 | Bub1-related kinase (BubR1) encodes a motif-rich protein with a C-terminal serine-threonine kinase domain. During prometaphase and metaphase, it plays important roles in spindle assembly checkpoint signalling, stabilization of kinetochore-microtuble attachments and chromosome alignment. It is also essential to maintain sister-chromatid cohesion during meiotic progression and for normal maintenance of Synaptonemal Complex in females. | Kinesin-like protein; Pavarotti (pav) encodes a microtubule motor protein from the Kinesin superfamily. It plays important roles during the mitotic cycle including spindle formation, cortical cytoskeleton reorganization and cytokinesis. It also negatively regulates Wnt activity. | 0.905 |
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