STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Gbs-70EProtein phosphatase 1 regulatory subunit; Glycogen binding subunit 70E (Gbs-70E) is one of the glycogen binding subunits of protein phosphatase 1 (Pp1) that interacts with all of the known Pp1 catalytic subunits (encoded by Pp1-87B, flw, Pp1alpha-96A, and Pp1-13C). The product of Gbs-70E is involved in the regulation of glycogen metabolism, and plays a role in the egg development. (384 aa)    
Predicted Functional Partners:
GlyS
Glycogen synthase (GlyS) encodes a glycosyltransferase that catalyzes linkage of glucose monomers into glycogen. Regulation of the product of GlyS activity by glucose 6-phosphate and phosphorylation helps control cellular glycogen levels.
   
 0.954
Pp1alpha-96A
Serine/threonine-protein phosphatase alpha-1 isoform; Protein phosphatase 1alpha at 96A (Pp1alpha-96A) encodes a phosphatase involved in the regulation of Hedgehog and Wnt signaling pathways.
   
 0.877
Pp1-87B
Serine/threonine-protein phosphatase alpha-2 isoform; Is essential for the regulation of mitotic chromosomal segregation as well as regulation of chromatin condensation during interphase; Belongs to the PPP phosphatase family. PP-1 subfamily.
   
 0.870
Pp1-13C
Serine/threonine-protein phosphatase alpha-3 isoform; Protein phosphatase 1 at 13C (Pp1-13C) encodes a phosphatase involved in hedgehog signaling regulation and sperm competition.
    
 0.855
Gyg
Glycogenin, isoform E; Glycogenin glucosyltransferase activity. It is involved in the biological process described with: glycogen biosynthetic process.
   
 0.851
Gbs-76A
Glycogen-binding subunit 76A; Protein phosphatase 1 binding; glycogen binding. It is involved in the biological process described with: regulation of glycogen biosynthetic process.
  
0.800
flw
Serine/threonine-protein phosphatase beta isoform; Required for cell adhesion in non-muscle tissues and in maintenance of muscle attachment. Vital for larval development. Belongs to the PPP phosphatase family. PP-1 subfamily.
   
 
 0.696
lute
Lute, isoform D; Lute (lute) encodes a protein involved in neurogenesis.
      
 0.626
PpN58A
Protein serine/threonine phosphatase activity. It is involved in the biological process described with: protein dephosphorylation; Belongs to the PPP phosphatase family.
    
 0.612
PpD5
Protein serine/threonine phosphatase activity. It is involved in the biological process described with: protein dephosphorylation; Belongs to the PPP phosphatase family.
    
 0.610
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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