STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EbpEjaculatory bulb-specific protein 1; Major protein component of the posterior mating plug. Accessory gland proteins constitute, or are required for formation of the anterior mating plug. Posterior mating plug forms before sperm transfer and the anterior mating plug is formed after the start of mating. (377 aa)    
Predicted Functional Partners:
EbpII
Ejaculatory bulb-specific protein 2; Protein component of the posterior mating plug.
   
  
 0.929
EbpIII
Ejaculatory bulb-specific protein 3; Protein component of the posterior mating plug.
      
 0.784
Acp36DE
Accessory gland protein Acp36DE; Responsible for physiological and behavioral changes in mated female flies. Associates with sperm and localizes to specific regions of the female reproductive tract, including the sperm storage organs. It accelerates sperm accumulation into storage but does not mediate the entry of the first sperm into storage. Once sperm storage has initiated it seems to act as a guidance factor helping subsequent sperm move into storage, a corral concentrating sperm around the SSO entrances and/or a trigger for responses within the female that accelerate storage of sperm.
   
 
 0.746
Sfp60F
Seminal fluid protein 60F, isoform A; It is involved in the biological process described with: multicellular organism reproduction.
   
  
 0.740
Sfp87B
Seminal fluid protein 87B; It is involved in the biological process described with: multicellular organism reproduction.
   
  
 0.707
Sfp24Bb
Seminal fluid protein 24Bb; Serine-type endopeptidase inhibitor activity. It is involved in the biological process described with: multicellular organism reproduction.
   
  
 0.702
Mst57Da
Male-specific RNA 57Da (Mst57Da) encodes a peptide that is produced by the male accessory glands and transferred to females during mating. Its proline-rich peptide composition suggests a possible role as an antimicrobial peptide.
   
  
 0.701
Acp29AB
Accessory gland protein 29AB (Acp29AB) encodes a predicted C-type lectin that is produced by the male accessory glands and transferred to females during mating. After transfer to mated females, the Acp29AB product is detected in sperm storage organs and in the hemolymph. It plays a role in retention of sperm in storage and sperm competition.
   
 
 0.676
Mst57Dc
Male-specific transcript 57Dc (Mst57Dc) encodes a peptide produced by the male accessory glands and transferred to females during mating.
   
  
 0.672
Acp62F
Accessory gland protein Acp62F; Responsible for physiological and behavioral changes in mated female flies. May contribute to the toxicity of seminal fluid and the decreased life-span of mated females. May also affect neuromuscular events after mating concerning sperm storage and egg release.
   
  
 0.667
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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