node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG8641 | Ca-alpha1T | FBpp0305568 | FBpp0306997 | MIP08469p; GTPase activity; GTP binding. It is involved in the biological process described with: signal transduction. | Ca[2+]-channel protein alpha[[1]] subunit T (Ca-alpha1T) encodes an alpha 1 subunit of a T-type like voltage gated calcium channel. It mediates a low voltage activated transient calcium current in antennal lobe projection neurons and wing motoneurons that is sensitive to amiloride. | 0.516 |
CG8641 | Lrrk | FBpp0305568 | FBpp0306703 | MIP08469p; GTPase activity; GTP binding. It is involved in the biological process described with: signal transduction. | Leucine-rich repeat kinase (Lrrk) encodes a large Ser/Thr kinase involved in mRNA translational control, cytoskeleton regulation, vesicle trafficking, autophagy, and immune response. | 0.750 |
CG8641 | Nf1 | FBpp0305568 | FBpp0084326 | MIP08469p; GTPase activity; GTP binding. It is involved in the biological process described with: signal transduction. | Neurofibromin 1 (Nf1) encodes a protein that functions as a GTPase activating protein for the products of Ras85D and Ras64B in the larval and adult nervous system. Loss of Nf1 results in excess Ras-Raf-ERK signaling and to a non-cell-autonomous cAMP/PKA signaling defect. The product of Nf1 contributes to postembryonic growth, learning/memory, and circadian rhythm. | 0.576 |
CG8641 | Pka-C3 | FBpp0305568 | FBpp0075283 | MIP08469p; GTPase activity; GTP binding. It is involved in the biological process described with: signal transduction. | cAMP-dependent protein kinase catalytic subunit 3; Does not have an essential role in development. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. | 0.527 |
CG8641 | Raf | FBpp0305568 | FBpp0310458 | MIP08469p; GTPase activity; GTP binding. It is involved in the biological process described with: signal transduction. | Raf homolog serine/threonine-protein kinase Raf; Serine/threonine kinase required in the early embryo for the formation of terminal structure. Also required during the proliferation of imaginal cells. May act downstream of Ras85D in the tor signal transduction pathway. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. | 0.549 |
CG8641 | Rbp6 | FBpp0305568 | FBpp0112339 | MIP08469p; GTPase activity; GTP binding. It is involved in the biological process described with: signal transduction. | RNA-binding protein 6 (Rbp6) encodes a paralog of the RNA-binding protein encoded by msi. In contrast to msi, Rbp6 mutants are viable and fertile, with only a slight delay in eclosion. The product of Rbp6 may have roles in response to fungal infection and aggressive behavior. | 0.617 |
CG8641 | Sytalpha | FBpp0305568 | FBpp0292346 | MIP08469p; GTPase activity; GTP binding. It is involved in the biological process described with: signal transduction. | Synaptotagmin alpha, isoform B. | 0.539 |
CG8641 | cmpy | FBpp0305568 | FBpp0294030 | MIP08469p; GTPase activity; GTP binding. It is involved in the biological process described with: signal transduction. | Crimpy, isoform C; BMP binding; insulin-like growth factor binding. | 0.625 |
CG8641 | mamo | FBpp0305568 | FBpp0311880 | MIP08469p; GTPase activity; GTP binding. It is involved in the biological process described with: signal transduction. | Maternal gene required for meiosis (mamo) encodes a zinc finger C2H2 transcription factor enriched in embryonic primordial germ cells. It is required for functional gamete production. | 0.526 |
CG8641 | norpA | FBpp0305568 | FBpp0290690 | MIP08469p; GTPase activity; GTP binding. It is involved in the biological process described with: signal transduction. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes (By similarity). Essential component of the phototransduction pathway. Essential downstream component of a hh-signaling pathway which regulates the Duox-dependent gut immune response to bacterial uracil; required for the activation of Cad99C and consequently Cad99C-dependent endosome formation, which is essential for the Duox-dependent product [...] | 0.514 |
Ca-alpha1T | CG8641 | FBpp0306997 | FBpp0305568 | Ca[2+]-channel protein alpha[[1]] subunit T (Ca-alpha1T) encodes an alpha 1 subunit of a T-type like voltage gated calcium channel. It mediates a low voltage activated transient calcium current in antennal lobe projection neurons and wing motoneurons that is sensitive to amiloride. | MIP08469p; GTPase activity; GTP binding. It is involved in the biological process described with: signal transduction. | 0.516 |
Ca-alpha1T | Rbp6 | FBpp0306997 | FBpp0112339 | Ca[2+]-channel protein alpha[[1]] subunit T (Ca-alpha1T) encodes an alpha 1 subunit of a T-type like voltage gated calcium channel. It mediates a low voltage activated transient calcium current in antennal lobe projection neurons and wing motoneurons that is sensitive to amiloride. | RNA-binding protein 6 (Rbp6) encodes a paralog of the RNA-binding protein encoded by msi. In contrast to msi, Rbp6 mutants are viable and fertile, with only a slight delay in eclosion. The product of Rbp6 may have roles in response to fungal infection and aggressive behavior. | 0.429 |
Ca-alpha1T | cmpy | FBpp0306997 | FBpp0294030 | Ca[2+]-channel protein alpha[[1]] subunit T (Ca-alpha1T) encodes an alpha 1 subunit of a T-type like voltage gated calcium channel. It mediates a low voltage activated transient calcium current in antennal lobe projection neurons and wing motoneurons that is sensitive to amiloride. | Crimpy, isoform C; BMP binding; insulin-like growth factor binding. | 0.416 |
Lrrk | CG8641 | FBpp0306703 | FBpp0305568 | Leucine-rich repeat kinase (Lrrk) encodes a large Ser/Thr kinase involved in mRNA translational control, cytoskeleton regulation, vesicle trafficking, autophagy, and immune response. | MIP08469p; GTPase activity; GTP binding. It is involved in the biological process described with: signal transduction. | 0.750 |
Nf1 | CG8641 | FBpp0084326 | FBpp0305568 | Neurofibromin 1 (Nf1) encodes a protein that functions as a GTPase activating protein for the products of Ras85D and Ras64B in the larval and adult nervous system. Loss of Nf1 results in excess Ras-Raf-ERK signaling and to a non-cell-autonomous cAMP/PKA signaling defect. The product of Nf1 contributes to postembryonic growth, learning/memory, and circadian rhythm. | MIP08469p; GTPase activity; GTP binding. It is involved in the biological process described with: signal transduction. | 0.576 |
Nf1 | Raf | FBpp0084326 | FBpp0310458 | Neurofibromin 1 (Nf1) encodes a protein that functions as a GTPase activating protein for the products of Ras85D and Ras64B in the larval and adult nervous system. Loss of Nf1 results in excess Ras-Raf-ERK signaling and to a non-cell-autonomous cAMP/PKA signaling defect. The product of Nf1 contributes to postembryonic growth, learning/memory, and circadian rhythm. | Raf homolog serine/threonine-protein kinase Raf; Serine/threonine kinase required in the early embryo for the formation of terminal structure. Also required during the proliferation of imaginal cells. May act downstream of Ras85D in the tor signal transduction pathway. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. | 0.619 |
Pka-C3 | CG8641 | FBpp0075283 | FBpp0305568 | cAMP-dependent protein kinase catalytic subunit 3; Does not have an essential role in development. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. | MIP08469p; GTPase activity; GTP binding. It is involved in the biological process described with: signal transduction. | 0.527 |
Raf | CG8641 | FBpp0310458 | FBpp0305568 | Raf homolog serine/threonine-protein kinase Raf; Serine/threonine kinase required in the early embryo for the formation of terminal structure. Also required during the proliferation of imaginal cells. May act downstream of Ras85D in the tor signal transduction pathway. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. | MIP08469p; GTPase activity; GTP binding. It is involved in the biological process described with: signal transduction. | 0.549 |
Raf | Nf1 | FBpp0310458 | FBpp0084326 | Raf homolog serine/threonine-protein kinase Raf; Serine/threonine kinase required in the early embryo for the formation of terminal structure. Also required during the proliferation of imaginal cells. May act downstream of Ras85D in the tor signal transduction pathway. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. | Neurofibromin 1 (Nf1) encodes a protein that functions as a GTPase activating protein for the products of Ras85D and Ras64B in the larval and adult nervous system. Loss of Nf1 results in excess Ras-Raf-ERK signaling and to a non-cell-autonomous cAMP/PKA signaling defect. The product of Nf1 contributes to postembryonic growth, learning/memory, and circadian rhythm. | 0.619 |
Rbp6 | CG8641 | FBpp0112339 | FBpp0305568 | RNA-binding protein 6 (Rbp6) encodes a paralog of the RNA-binding protein encoded by msi. In contrast to msi, Rbp6 mutants are viable and fertile, with only a slight delay in eclosion. The product of Rbp6 may have roles in response to fungal infection and aggressive behavior. | MIP08469p; GTPase activity; GTP binding. It is involved in the biological process described with: signal transduction. | 0.617 |