STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG5399GH25158p. (218 aa)    
Predicted Functional Partners:
CG31213
Uncharacterized protein, isoform B; Lipid transporter activity; ATPase-coupled transmembrane transporter activity; ATP binding; ATPase activity. It is involved in the biological process described with: transmembrane transport; lipid transport.
      
 0.915
JYalpha
Sodium/potassium-transporting ATPase subunit alpha; JYalpha (JYalpha) is a gene essential for male fertility as mutants produce immotile sperm.
      
 0.795
kl-2
Male fertility factor kl2; ATP binding; ATPase activity; dynein intermediate chain binding; dynein light intermediate chain binding; ATP-dependent microtubule motor activity, minus-end-directed. It is involved in the biological process described with: cilium movement; microtubule-based movement.
      
 0.666
CG5213
AT22957p; mRNA binding; RNA binding. It is involved in the biological process described with: regulation of alternative mRNA splicing, via spliceosome; mRNA cis splicing, via spliceosome.
      
 0.664
kl-3
Male fertility factor kl3 (kl-3) encodes a dynein heavy chain that is a component of a microtubule motor complex. This motor activity is essential only for spermatogenesis. Lack of kl-3 results in loss of the axonemal out dynein arms in the spermatid tail.
      
 0.656
CG15347
LP18071p.
   
    0.641
CG13321
RE03883p.
   
    0.638
Tsp29Fb
Tetraspanin.
   
    0.562
CG9568
LP01634p.
   
    0.556
Rb97D
Ribonucleoprotein RB97D; Required for spermatogenesis. Could be required to process a specific transcript essential for spermatogenesis.
      
 0.531
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.