STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG9981ATPase-coupled intramembrane lipid transporter activity; magnesium ion binding; ATP binding. It is involved in the biological process described with: phospholipid translocation; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1060 aa)    
Predicted Functional Partners:
CDC50
CDC50, isoform A; It is involved in the biological process described with: phospholipid transport; Belongs to the CDC50/LEM3 family.
   
 
 0.885
CG31729
ATP binding; magnesium ion binding; ATPase-coupled intramembrane lipid transporter activity. It is involved in the biological process described with: retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; phospholipid translocation; endocytosis; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
    
0.537
CG45062
Uncharacterized protein, isoform A; ATPase activity; nucleotide binding; calcium transmembrane transporter activity, phosphorylative mechanism; proton-exporting ATPase activity, phosphorylative mechanism. It is involved in the biological process described with: calcium ion transmembrane transport; cellular calcium ion homeostasis.
  
     0.531
CG45063
Cation_ATPase_N domain-containing protein.
  
     0.526
CG4301
ATPase-coupled intramembrane lipid transporter activity; ATP binding; magnesium ion binding. It is involved in the biological process described with: phospholipid translocation; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
  
 
 
0.481
ATP8A
ATP binding; magnesium ion binding; ATPase-coupled intramembrane lipid transporter activity. It is involved in the biological process described with: phospholipid translocation; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
  
  
0.466
CG33298
Magnesium ion binding; ATP binding; ATPase-coupled intramembrane lipid transporter activity. It is involved in the biological process described with: phospholipid translocation; Golgi organization; intracellular protein transport; response to endoplasmic reticulum stress; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
  
  
0.459
ATP8B
ATPase 8B (ATP8B) encodes a phospholipid flippase involved in olfaction; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
  
  
0.443
aux
Auxilin, isoform A; Auxilin (aux) encodes a co-factor for the ATPase Hsc70 that regulates Clathrin dynamics. It regulates Notch signaling, eye morphogenesis, sperm individualization and neuron death.
    
 
 0.420
Sec63
Secretory 63; Protein transmembrane transporter activity; RNA binding. It is involved in the biological process described with: SRP-dependent cotranslational protein targeting to membrane; posttranslational protein targeting to endoplasmic reticulum membrane; posttranslational protein targeting to membrane, translocation.
   
 
 0.409
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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