STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GA21084Ubiquitin carboxyl-terminal hydrolase calypso; Polycomb group (PcG) protein. Catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-118' (H2AK118ub1). Does not deubiquitinate monoubiquitinated histone H2B. Required to maintain the transcriptionally repressive state of homeotic genes throughout development. The PR-DUB complex has weak or no activity toward 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity); Belongs to the peptidase C12 family. BAP1 subfamily (475 aa)    
Predicted Functional Partners:
GA24730
annotation not available
    
 
 0.811
GA20570
Uncharacterized protein, isoform A; Enzyme regulator activity. It is involved in the biological process described with: regulation of protein catabolic process
   
 
 0.779
GA22734
annotation not available
   
 
 0.761
GA12224
annotation not available
   
 
 0.761
GA14323
annotation not available
   
 
 0.754
GA20997
Uncharacterized protein, isoform A; Ubiquitin-specific protease activity; calcium ion binding. It is involved in the biological process described with: ubiquitin-dependent protein catabolic process; Belongs to the peptidase C19 family
   
 
 0.727
GA20484
Uncharacterized protein; It is involved in the biological process described with: ubiquitin-dependent protein catabolic process
   
 
 0.702
GA10344
Uncharacterized protein; Enzyme regulator activity. It is involved in the biological process described with: regulation of protein catabolic process
   
 
 0.695
GA11303
annotation not available
   
 
 0.690
GA24424
annotation not available
   
 
 0.668
Your Current Organism:
Drosophila pseudoobscura
NCBI taxonomy Id: 7237
Other names: D. pseudoobscura, Drosophila pseudoobscura
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