STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y3NMI1tRNA-dihydrouridine synthase; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs; Belongs to the dus family. (320 aa)    
Predicted Functional Partners:
A0A1Y3MNP0
AA_TRNA_LIGASE_II domain-containing protein.
  
 
 0.983
A0A1Y3N5F6
tRNA (guanine(46)-N(7))-methyltransferase.
  
 
 0.700
SPB1
AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
  
  
 0.679
A0A1Y3NGC5
tRNA (guanine(26)-N(2))-dimethyltransferase.
   
 
 0.668
A0A1Y3NKZ3
Uncharacterized protein.
   
    0.666
A0A1Y3MVU5
tRNA pseudouridine synthase.
  
 
 0.658
A0A1Y3NE06
Uncharacterized protein.
  
 
 0.658
A0A1Y3MWF5
Uncharacterized protein.
   
  
 0.657
A0A1Y3MNP7
RRM domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
  
  
 0.639
TRM82
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family.
   
 
 0.625
Your Current Organism:
Piromyces sp. E2
NCBI taxonomy Id: 73868
Other names: P. sp. E2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.