STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UYA_22720Cd(II)/Pb(II)-responsive transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa)    
Predicted Functional Partners:
UYA_16960
MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 
 0.790
UYA_22715
4-deoxy-4-formamido-L-arabinose-phospho-UDP deformylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.653
UYA_22725
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.590
UYA_22710
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.554
UYA_15720
Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.538
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
  
 
 0.538
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.462
UYA_18990
Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.433
UYA_00515
Amino acid ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.410
UYA_21550
Sodium:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.406
Your Current Organism:
Pseudomonas alcaliphila
NCBI taxonomy Id: 741155
Other names: P. alcaliphila JAB1, Pseudomonas alcaliphila JAB1, Pseudomonas alcaliphila str. JAB1, Pseudomonas alcaliphila strain JAB1, Pseudomonas sp. JAB1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.