STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJZ66207.1Phosphoserine phosphatase SerB. (408 aa)    
Predicted Functional Partners:
hisI
Histidine biosynthesis HisIE; In the N-terminal section; belongs to the PRA-CH family.
  
  
 0.912
EJZ65089.1
Aspartate kinase.
  
 
 0.910
serC
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
  
 
 0.899
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.895
hisB
Histidinol-phosphatase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
  
  
 0.803
EJZ64904.1
L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
   
 
 0.774
EJZ64890.1
Cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.765
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
    
 0.761
EJZ65964.1
Hypothetical protein.
    
 0.760
EJZ64549.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.760
Your Current Organism:
Barnesiella intestinihominis
NCBI taxonomy Id: 742726
Other names: B. intestinihominis YIT 11860, Barnesiella intestinihominis YIT 11860, Barnesiella intestinihominis str. YIT 11860, Barnesiella intestinihominis strain YIT 11860
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