STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrDDihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. (304 aa)    
Predicted Functional Partners:
pyrK
Hypothetical protein; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
 0.999
EJZ66273.1
Hypothetical protein.
 
 0.980
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
 0.958
EJZ62954.1
Dihydroorotase, multifunctional complex type.
 
 0.957
EJZ63773.1
Carbamoyl-phosphate synthase, large subunit.
  
 0.951
pyrF
Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
 
 0.948
EJZ66272.1
Glutamate synthase (NADPH), homotetrameric.
 0.940
pyrB
Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
 
 0.930
carA
Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family.
  
  
 0.850
pheT
phenylalanine-tRNA ligase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.838
Your Current Organism:
Barnesiella intestinihominis
NCBI taxonomy Id: 742726
Other names: B. intestinihominis YIT 11860, Barnesiella intestinihominis YIT 11860, Barnesiella intestinihominis str. YIT 11860, Barnesiella intestinihominis strain YIT 11860
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