STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lpdA1Dihydrolipoyl dehydrogenase; Has chromate reductase activity. (461 aa)    
Predicted Functional Partners:
ADW20771.1
Dihydrolipoamideacetyltransferase component of pyruvate dehydrogenase complex.
 0.999
ADW20876.1
Dihydrolipoamideacetyltransferase component of pyruvate dehydrogenase complex.
 0.999
acoB
2-oxoisovalerate dehydrogenase, subunit beta; Bckdhe1-beta; branched-chain alpha-keto acid dehydrogenase e1 component beta chain.
 
 0.998
sucB
Dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.997
acoA
2-oxoisovalerate dehydrogenase, subunit alpha; Bckdhe1-alpha; branched-chain alpha-keto acid dehydrogenase e1 component alpha chain.
 
 
 0.996
pdhB
Pyruvate dehydrogenase E1 component, subunit beta; 36 kDa subunit.
 
 0.994
sucA
Oxoglutarate dehydrogenase, E1 component; Succinyl-transferring.
 
 0.990
pdhA
Pyruvate dehydrogenase E1 component, subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 
 
 0.986
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
  
 0.976
gcvT
Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.
 
 0.967
Your Current Organism:
Thermus scotoductus
NCBI taxonomy Id: 743525
Other names: T. scotoductus SA-01, Thermus scotoductus SA-01, Thermus scotoductus str. SA-01, Thermus scotoductus strain SA-01, Thermus sp. SA-01
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