STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG45609.1PFAM: Protein of unknown function DUF606; KEGG: mil:ML5_1112 hypothetical protein. (339 aa)    
Predicted Functional Partners:
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
    0.614
pyrF
PFAM: Orotidine 5'-phosphate decarboxylase, core; TIGRFAM: Orotidine 5'-phosphate decarboxylase, subfamily 2, core; HAMAP: Orotidine 5'-phosphate decarboxylase; KEGG: xce:Xcel_1713 orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
    0.608
AEG45610.1
Cyclase/dehydrase; PFAM: Streptomyces cyclase/dehydrase; KEGG: kfl:Kfla_0716 cyclase/dehydrase.
       0.574
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
    0.571
AEG44174.1
KEGG: xce:Xcel_1439 hypothetical protein.
  
     0.526
AEG43389.1
RDD domain containing protein; PFAM: RDD; Forkhead-associated; KEGG: xce:Xcel_0488 FHA domain containing protein.
  
     0.510
AEG44175.1
PFAM: DNA-repair protein, UmuC-like; KEGG: xce:Xcel_1440 hypothetical protein.
 
     0.477
AEG44745.1
KEGG: apn:Asphe3_12530 hypothetical protein.
  
     0.458
AEG43549.1
KEGG: xce:Xcel_0736 PE-PGRS family protein.
  
     0.431
pyrC
Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
  
    0.422
Your Current Organism:
Isoptericola variabilis
NCBI taxonomy Id: 743718
Other names: I. variabilis 225, Isoptericola variabilis 225, Isoptericola variabilis str. 225, Isoptericola variabilis strain 225
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