STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEF22046.1PFAM: DNA ligase, ATP-dependent, central; DNA ligase, ATP-dependent, C-terminal; KEGG: psa:PST_2662 ATP-dependent DNA ligase. (579 aa)    
Predicted Functional Partners:
AEF22045.1
Beta-lactamase domain protein; PFAM: Beta-lactamase-like; KEGG: pfs:PFLU1313 hypothetical protein.
 0.988
AEF22048.1
Metallophosphoesterase; PFAM: Metallo-dependent phosphatase; KEGG: pmy:Pmen_2193 ICC-like putative phosphoesterase.
 
   
 0.981
AEF22047.1
DEAD/H associated domain protein; KEGG: psa:PST_2663 DEAD-box ATP dependent DNA helicase; PFAM: DEAD/H associated; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal.
 
    0.955
ligA
DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
    
 0.933
AEF19989.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.917
ligB
DNA ligase (NAD(+)); Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
    
 0.914
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.866
AEF24088.1
KEGG: pst:PSPTO_2621 DNA polymerase II; PFAM: DNA-directed DNA polymerase, family B, conserved region; DNA-directed DNA polymerase, family B, exonuclease domain; SMART: DNA-directed DNA polymerase, family B.
   
 0.723
AEF22688.1
TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: psp:PSPPH_1647 DNA polymerase III subunit delta'.
   
 0.712
AEF22258.1
KEGG: pmy:Pmen_2775 DNA topoisomerase.
 
 
 
 0.657
Your Current Organism:
Pseudomonas fulva
NCBI taxonomy Id: 743720
Other names: P. fulva 12-X, Pseudomonas fulva 12-X, Pseudomonas fulva str. 12-X, Pseudomonas fulva strain 12-X
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.