STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV28643.1PFAM: Glutathione S-transferase domain; KEGG: sml:Smlt4504 putative glutathione S transferase; Belongs to the GST superfamily. (228 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.610
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.537
ADV28486.1
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: xal:XALc_0775 probable lactoylglutathione lyase protein.
 
    0.520
ADV28113.1
PFAM: Glutathione S-transferase domain; KEGG: sml:Smlt0950 putative glutathione S-transferase.
  
    0.508
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
      
 0.501
ADV28642.1
PFAM: Uncharacterised protein family UPF0114; KEGG: sml:Smlt4505 hypothetical protein.
       0.482
ADV27598.1
PFAM: Glutathione S-transferase domain; KEGG: xca:xccb100_2880 putative glutathione transferase.
  
    0.480
ADV27291.1
PFAM: Glutathione S-transferase domain; KEGG: xcb:XC_1829 putative substrate binding pocket (H-site); other site.
  
   
 0.479
lysS
lysyl-tRNA synthetase; KEGG: xcb:XC_2336 motif 3; other site; TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; Belongs to the class-II aminoacyl-tRNA synthetase family.
   
  0.456
ADV28044.1
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: xca:xccb100_1582 putative glutathione reductase.
  
 
 0.445
Your Current Organism:
Pseudoxanthomonas suwonensis 111
NCBI taxonomy Id: 743721
Other names: P. suwonensis 11-1, Pseudoxanthomonas suwonensis 11-1, Pseudoxanthomonas suwonensis str. 11-1, Pseudoxanthomonas suwonensis strain 11-1
Server load: medium (66%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.