STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (324 aa)    
Predicted Functional Partners:
pgi
HAMAP: Phosphoglucose isomerase (PGI); KEGG: phe:Phep_0280 glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase (PGI); Belongs to the GPI family.
  
 0.981
ADZ80528.1
Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
 
 
 0.945
ADZ78746.1
SMART: Transketolase-like, pyrimidine-binding domain; TIGRFAM: Transketolase, bacterial-like; KEGG: sli:Slin_2594 transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; Belongs to the transketolase family.
  
 
 0.921
fbp
HAMAP: Fructose-1,6-bisphosphatase class 1/Sedoheputulose-1,7-bisphosphatase; KEGG: phe:Phep_2970 inositol phosphatase/fructose-16-bisphosphatase; PFAM: Fructose-1,6-bisphosphatase class 1/Sedoheputulose-1,7-bisphosphatase.
    
 0.919
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
  
 
 0.915
tal-2
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.915
ADZ81292.1
Fructokinase; KEGG: fjo:Fjoh_4043 ribokinase-like domain-containing protein; PFAM: Carbohydrate/purine kinase.
  
 
 0.909
ADZ78206.1
PFAM: Mannose-6-phosphate isomerase, type II, C-terminal; KEGG: phe:Phep_3485 hypothetical protein.
    
 0.903
ADZ79166.1
Transketolase; KEGG: phe:Phep_2799 transketolase domain protein; PFAM: Transketolase, N-terminal.
    
 0.902
pfkA-2
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
  
 
0.902
Your Current Organism:
Sphingobacterium sp. 21
NCBI taxonomy Id: 743722
Other names: S. sp. 21
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.