STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYB_01485COG0846 NAD-dependent protein deacetylases, SIR2 family. (291 aa)    
Predicted Functional Partners:
MYB_01475
COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.
   
   0.848
lplA-1
COG0095 Lipoate-protein ligase A.
  
    0.840
gcvH
COG0509 Glycine cleavage system H protein (lipoate-binding).
       0.830
MYB_01495
Oxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.
       0.830
dnaK-1
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.751
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
   
  0.708
MYB_01500
Lipase/esterase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
  
    0.664
gap
COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
 
 0.639
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.636
prs
Ribose-phosphate pyrophosphokinase; COG0462 Phosphoribosylpyrophosphate synthetase.
   
 
 0.621
Your Current Organism:
Mycoplasma bovoculi
NCBI taxonomy Id: 743966
Other names: M. bovoculi M165/69, Mycoplasma bovoculi ATCC 29104, Mycoplasma bovoculi M165/69, Mycoplasma bovoculi str. M165/69, Mycoplasma bovoculi strain M165/69
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