STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FoxpFoxP protein. (945 aa)    
Predicted Functional Partners:
A0A088AK75
WD_REPEATS_REGION domain-containing protein.
      
 0.762
A0A088AIQ0
Uncharacterized protein.
      
 0.727
Bgb
Uncharacterized protein.
    
 0.691
A0A088AIC5
Brix domain-containing protein.
      
 0.614
AmHO
Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase.
      
 0.610
A0A088AMU6
Uncharacterized protein.
      
 0.590
TyHyd
BH4_AAA_HYDROXYL_2 domain-containing protein.
      
 0.569
A0A088A8G9
Uncharacterized protein.
     
 0.558
MED8
Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.551
A0A088ASS4
C2H2-type domain-containing protein.
      
 0.550
Your Current Organism:
Apis mellifera
NCBI taxonomy Id: 7460
Other names: A. mellifera, Apis mellifica, European honey bee, Western honey bee, bee, honey bee, honeybee
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.