STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cact3Uncharacterized protein. (571 aa)    
Predicted Functional Partners:
Mcm5
DNA helicase; Belongs to the MCM family.
   
 0.997
Mcm3
DNA helicase.
   
 0.997
Mcm7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
 0.996
A0A088A2S4
DNA helicase; Belongs to the MCM family.
   
 0.995
LOC413064
DNA helicase; Belongs to the MCM family.
   
 0.990
LOC411640
DNA helicase; Belongs to the MCM family.
   
 0.981
LOC410442
MCM domain-containing protein; Belongs to the MCM family.
   
 0.970
A0A088AHE5
MCM domain-containing protein; Belongs to the MCM family.
   
 0.880
A0A088AW97
MCM_OB domain-containing protein.
   
 0.880
A0A088A4J3
Uncharacterized protein.
   
  
 0.837
Your Current Organism:
Apis mellifera
NCBI taxonomy Id: 7460
Other names: A. mellifera, Apis mellifica, European honey bee, Western honey bee, bee, honey bee, honeybee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.