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LOC724496 protein (Apis mellifera) - STRING interaction network
"LOC724496" - Adenylyltransferase and sulfurtransferase MOCS3 in Apis mellifera
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Known Interactions
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Predicted Interactions
gene neighborhood
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gene co-occurrence
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textmining
co-expression
protein homology
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LOC724496Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide t [...] (435 aa)    
Predicted Functional Partners:
Mocs2
Molybdopterin synthase 2 (381 aa)
   
  0.988
LOC551580
Ubiquitin-related modifier 1 homolog; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2- thiolation reaction by being thiocarboxylated (-COSH) at its C- terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress sp [...] (103 aa)
     
  0.974
LOC410039
Cysteine desulfurase-like protein (423 aa)
   
  0.973
LOC410867
Uncharacterized LOC410867 (1615 aa)
   
  0.924
GB19555-PA
Annotation not available (271 aa)
   
  0.887
LOC410838
Uncharacterized protein (239 aa)
     
  0.879
Ube2g1
Ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) (EC-6.3.2.19) (160 aa)
     
  0.879
UbcD2
Ubiquitin conjugating enzyme 2 (186 aa)
     
  0.877
UbcD6
Uncharacterized protein (151 aa)
     
  0.876
LOC408708
Ubiquitin-conjugating enzyme E2 S-like (212 aa)
     
  0.876
Your Current Organism:
Apis mellifera
NCBI taxonomy Id: 7460
Other names: A. mellifera, Anthophoridae, Apidae, Apinae, Apini, Apis, Apis mellifera, Apis mellifica, Apoidea, bee, bees, bumble bees and honey bees, honey bee, honey bees, honeybee
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