STRINGSTRING
MLH1 protein (Apis mellifera) - STRING interaction network
"MLH1" - mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) in Apis mellifera
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MLH1mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) (891 aa)    
Predicted Functional Partners:
spel1
DNA mismatch repair protein spellchecker 1; Component of the post-replicative DNA mismatch repair system (MMR) (856 aa)
 
  0.981
Msh6
DNA mismatch repair protein Msh6; Component of the post-replicative DNA mismatch repair system (MMR) (1129 aa)
 
  0.979
Ame.29400
Uncharacterized protein (550 aa)
   
0.974
GB17569
mutS protein homolog 4-like (907 aa)
   
  0.936
GB11065
Uncharacterized LOC726879 (981 aa)
   
  0.935
GB13205-PA
Uncharacterized protein (844 aa)
     
  0.906
LOC412308
Flap endonuclease 1; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. It enters the flap from the 5’-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a [...] (379 aa)
   
  0.904
LOC724240
Flap endonuclease GEN-like (713 aa)
   
  0.881
mus209
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase’s processibility during elongation of the leading strand (261 aa)
   
  0.880
Rad51
DNA repair protein Rad51 homolog (341 aa)
   
  0.867
Your Current Organism:
Apis mellifera
NCBI taxonomy Id: 7460
Other names: A. mellifera, Anthophoridae, Apidae, Apinae, Apini, Apis, Apis mellifera, Apis mellifica, Apoidea, bee, bees, bumble bees and honey bees, honey bee, honey bees, honeybee
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