pyrE protein (Pasteurella multocida) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

pyrE

annotation not available (214 aa)

Predicted Functional Partners:

pyrF

0.995

pyrD

0.966

rph

0.935

carA

0.922

carB

0.884

prs

0.836

guaA

0.823

purL

0.775

guaB

0.737

yajC

0.721

Your Current Organism:

Pasteurella multocida

NCBI taxonomy Id: 747
Other names: ATCC 43137, Bacterium multocidum, CCUG 17976, CCUG 17976 B, CCUG 43504, CIP 103286, DSM 16031, LMG 2851, Micrococcus gallicidus, NCTC 10322, P. multocida, Pasteurella cholerae-gallinarum, Pasteurella gallicida, Pasteurella multocida

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
carA	carB	DR93_349	DR93_352	CPSaseIIsmall- carbamoyl-phosphate synthase, small subunit	CPSaseII_lrg- carbamoyl-phosphate synthase, large subunit	0.999
carA	guaA	DR93_349	DR93_1768	CPSaseIIsmall- carbamoyl-phosphate synthase, small subunit	guaA_Nterm- GMP synthase (glutamine-hydrolyzing), N-terminal domain	0.496
carA	pyrD	DR93_349	DR93_1447	CPSaseIIsmall- carbamoyl-phosphate synthase, small subunit	pyrD_sub2- dihydroorotate dehydrogenase	0.663
carA	pyrE	DR93_349	DR93_58	CPSaseIIsmall- carbamoyl-phosphate synthase, small subunit	annotation not available	0.922
carA	pyrF	DR93_349	DR93_1637	CPSaseIIsmall- carbamoyl-phosphate synthase, small subunit	pyrF- orotidine 5’-phosphate decarboxylase	0.925
carB	carA	DR93_352	DR93_349	CPSaseII_lrg- carbamoyl-phosphate synthase, large subunit	CPSaseIIsmall- carbamoyl-phosphate synthase, small subunit	0.999
carB	guaA	DR93_352	DR93_1768	CPSaseII_lrg- carbamoyl-phosphate synthase, large subunit	guaA_Nterm- GMP synthase (glutamine-hydrolyzing), N-terminal domain	0.882
carB	guaB	DR93_352	DR93_1766	CPSaseII_lrg- carbamoyl-phosphate synthase, large subunit	IMP_dehydrog- inosine-5’-monophosphate dehydrogenase	0.839
carB	purL	DR93_352	DR93_879	CPSaseII_lrg- carbamoyl-phosphate synthase, large subunit	FGAM_synt- phosphoribosylformylglycinamidine synthase	0.907
carB	pyrD	DR93_352	DR93_1447	CPSaseII_lrg- carbamoyl-phosphate synthase, large subunit	pyrD_sub2- dihydroorotate dehydrogenase	0.827
carB	pyrE	DR93_352	DR93_58	CPSaseII_lrg- carbamoyl-phosphate synthase, large subunit	annotation not available	0.884
carB	pyrF	DR93_352	DR93_1637	CPSaseII_lrg- carbamoyl-phosphate synthase, large subunit	pyrF- orotidine 5’-phosphate decarboxylase	0.950
guaA	carA	DR93_1768	DR93_349	guaA_Nterm- GMP synthase (glutamine-hydrolyzing), N-terminal domain	CPSaseIIsmall- carbamoyl-phosphate synthase, small subunit	0.496
guaA	carB	DR93_1768	DR93_352	guaA_Nterm- GMP synthase (glutamine-hydrolyzing), N-terminal domain	CPSaseII_lrg- carbamoyl-phosphate synthase, large subunit	0.882
guaA	guaB	DR93_1768	DR93_1766	guaA_Nterm- GMP synthase (glutamine-hydrolyzing), N-terminal domain	IMP_dehydrog- inosine-5’-monophosphate dehydrogenase	0.999
guaA	prs	DR93_1768	DR93_1816	guaA_Nterm- GMP synthase (glutamine-hydrolyzing), N-terminal domain	annotation not available	0.895
guaA	purL	DR93_1768	DR93_879	guaA_Nterm- GMP synthase (glutamine-hydrolyzing), N-terminal domain	FGAM_synt- phosphoribosylformylglycinamidine synthase	0.983
guaA	pyrD	DR93_1768	DR93_1447	guaA_Nterm- GMP synthase (glutamine-hydrolyzing), N-terminal domain	pyrD_sub2- dihydroorotate dehydrogenase	0.888
guaA	pyrE	DR93_1768	DR93_58	guaA_Nterm- GMP synthase (glutamine-hydrolyzing), N-terminal domain	annotation not available	0.823
guaA	pyrF	DR93_1768	DR93_1637	guaA_Nterm- GMP synthase (glutamine-hydrolyzing), N-terminal domain	pyrF- orotidine 5’-phosphate decarboxylase	0.830

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