STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEE14699.1Lactate utilization protein B/C; COGs: COG1139 conserved hypothetical protein containing a ferredoxin-like domain; InterPro IPR003741:IPR001450:IPR004017; KEGG: hmo:HM1_0363 4fe-4S ferredoxin, iron-sulfur binding protein, putative; PFAM: Protein of unknown function DUF162; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Cysteine-rich region, CCG; SPTR: Putative uncharacterized protein; IMG reference gene:2504784476; PFAM: Cysteine-rich domain; Uncharacterised ACR, YkgG family COG1556; TIGRFAM: iron-sulfur cluster-binding protein. (722 aa)    
Predicted Functional Partners:
AEE14700.1
Lactate utilization protein B/C; COGs: COG1556 conserved hypothetical protein; InterPro IPR003741; KEGG: drm:Dred_0689 hypothetical protein; PFAM: Protein of unknown function DUF162; SPTR: Putative uncharacterized protein; IMG reference gene:2504784477; PFAM: Uncharacterised ACR, YkgG family COG1556.
 
 
 0.999
AEE14576.1
Lactate utilization protein B/C; COGs: COG1556 conserved hypothetical protein; InterPro IPR003741; KEGG: dba:Dbac_1728 protein of unknown function DUF162; PFAM: Protein of unknown function DUF162; SPTR: Putative uncharacterized protein; IMG reference gene:2504784344; PFAM: Uncharacterised ACR, YkgG family COG1556.
 
 
 0.995
AEE15206.1
Methyl-viologen-reducing hydrogenase delta subunit; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterPro IPR003953:IPR001450:IPR003813; KEGG: tye:THEYE_A1830 heterodisulfide reductase, subunit A/methylviologen reducing hydrogenase, subunit delta; PFAM: Methyl-viologen-reducing hydrogenase, delta subunit; Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Heterodisulfide reductase, subunit A/methylviologen reducing hydrogenase, subunit delta; IMG reference gene:2504785012; PFAM: [...]
  
 
 0.980
AEE14105.1
Glutamate synthase (NADPH); COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterPro IPR003953:IPR001450:IPR013027; KEGG: abi:Aboo_0977 FAD-dependent pyridine nucleotide-disulfide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; PRIAM: Glutamate synthase (NADPH); SPTR: FAD-dependent pyridine nucleotide-disulfide oxidoreductase; IMG reference gene:2504783843; PFAM: Pyridine nucleotide-disulphide oxidoredu [...]
  
 
 0.910
AEE15186.1
L-lactate transport; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
 
  
 0.835
AEE13983.1
COGs: COG0374 Ni Fe-hydrogenase I large subunit; InterPro IPR001501; KEGG: tjr:TherJR_0258 nickel-dependent hydrogenase large subunit; PFAM: Nickel-dependent hydrogenase, large subunit; PRIAM: Cytochrome-c3 hydrogenase; SPTR: Nickel-dependent hydrogenase large subunit; IMG reference gene:2504783714; PFAM: Nickel-dependent hydrogenase.
  
 
 0.816
AEE15121.1
COGs: COG1908 Coenzyme F420-reducing hydrogenase delta subunit; InterPro IPR003813:IPR019575; KEGG: tye:THEYE_A1728 F420-non-reducing hydrogenase vhc iron-sulfur subunit D; PFAM: Methyl-viologen-reducing hydrogenase, delta subunit; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; SPTR: F420-non-reducing hydrogenase vhc iron-sulfur subunit D; IMG reference gene:2504784921; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Methyl-viologen-reducing hydrogenase, delta subunit.
  
 
 0.811
AEE15185.1
L-lactate permease, putative; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
 
  
 0.785
AEE14104.1
4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterPro IPR003953:IPR001450; KEGG: adg:Adeg_1885 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; SPTR: Fumarate reductase/succinate dehydrogenase flavoprotein domain protein; IMG reference gene:2504783842; PFAM: Pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S binding domain.
  
 
 0.783
AEE14949.1
4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterPro IPR001450; KEGG: tye:THEYE_A1371 CoB--CoM heterodisulfide reductase iron-sulfur subunit A, selenocysteine-containing; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: CoB--CoM heterodisulfide reductase iron-sulfur subunit A, selenocysteine-containing; IMG reference gene:2504784742; PFAM: 4Fe-4S binding domain.
  
 
 0.783
Your Current Organism:
Thermodesulfobium narugense
NCBI taxonomy Id: 747365
Other names: T. narugense DSM 14796, Thermodesulfobium narugense DSM 14796, Thermodesulfobium narugense Na82, Thermodesulfobium narugense str. DSM 14796, Thermodesulfobium narugense strain DSM 14796, sulfate-reducing bacterium Na82
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.