STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADY61208.1COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR012310: IPR012309; KEGG: gau:GAU_3403 ATP-dependent DNA ligase; PFAM: ATP dependent DNA ligase, central; ATP dependent DNA ligase, C-terminal; SPTR: ATP-dependent DNA ligase; PFAM: ATP dependent DNA ligase domain; DNA ligase N terminus; ATP dependent DNA ligase C terminal region. (546 aa)    
Predicted Functional Partners:
ADY61207.1
RNA processing exonuclease; COGs: COG1236 exonuclease of the beta-lactamase fold involved in RNA processing; KEGG: ppu:PP_1106 RNA processing exonuclease; SPTR: Putative uncharacterized protein.
 
 0.996
ADY59950.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.981
ADY61210.1
Metallophosphoesterase; COGs: COG1407 ICC-like phosphoesterase; InterPro IPR004843; KEGG: plm:Plim_0355 metallophosphoesterase; PFAM: Metallophosphoesterase; SPTR: Metallophosphoesterase.
 
   
 0.955
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.952
ADY61209.1
DEAD/H associated domain protein; COGs: COG1201 Lhr-like helicase; InterPro IPR014001: IPR001650: IPR011545: IPR013701; KEGG: plm:Plim_3000 DEAD/H associated domain protein; PFAM: DEAD/H associated; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: DEAD/H associated domain protein; PFAM: Helicase conserved C-terminal domain; DEAD/H associated; DEAD/DEAH box helicase.
 
    0.951
ADY62115.1
PHP domain protein; COGs: COG1796 DNA polymerase IV (family X); InterPro IPR002054: IPR003141: IPR004013; KEGG: plm:Plim_1730 DNA-directed DNA polymerase; PFAM: PHP, C-terminal; SMART: DNA-directed DNA polymerase, family X; Polymerase/histidinol phosphatase, N-terminal; SPTR: DNA polymerase beta family protein; PFAM: PHP domain.
  
 0.925
ligA
DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
    
 0.912
ADY60560.1
Endonuclease/exonuclease/phosphatase; InterPro IPR005135; KEGG: amr:AM1_G0049 hypothetical protein; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: Putative uncharacterized protein; PFAM: Endonuclease/Exonuclease/phosphatase family.
  
 
 0.883
ADY58759.1
KEGG: slp:Slip_1276 hypothetical protein; SPTR: Putative uncharacterized protein.
   
 0.819
ADY61218.1
Metallophosphoesterase; COGs: COG0420 DNA repair exonuclease; InterPro IPR004843; KEGG: scl:sce7166 DNA repair exonuclease family protein; PFAM: Metallophosphoesterase; SPTR: Putative exonuclease; PFAM: Calcineurin-like phosphoesterase.
   
 0.678
Your Current Organism:
Rubinisphaera brasiliensis
NCBI taxonomy Id: 756272
Other names: Planctomyces brasiliensis ATCC 49424, Planctomyces brasiliensis DSM 5305, Planctomyces brasiliensis str. DSM 5305, Planctomyces brasiliensis strain DSM 5305, R. brasiliensis DSM 5305, Rubinisphaera brasiliensis DSM 5305
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