STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BNA13-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (180 aa)    
Predicted Functional Partners:
BNA5
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.
  
 
 0.987
CTHT_0030860
Catalase domain-containing protein.
   
 
  0.908
CTHT_0024820
Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family.
   
 
  0.908
CTHT_0021320
Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family.
   
 
  0.908
katG
Catalase-peroxidase; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
     
 0.901
BNA4
Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.
  
  
 0.843
CTHT_0070690
Amidohydro-rel domain-containing protein; Belongs to the metallo-dependent hydrolases superfamily.
   
 
 0.734
CTHT_0064560
Amidohydro-rel domain-containing protein; Belongs to the metallo-dependent hydrolases superfamily.
   
 
 0.614
CTHT_0058370
Nicotinate phosphoribosyltransferase-like protein.
   
 
 0.587
CTHT_0066730
Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.
      
 0.563
Your Current Organism:
Chaetomium thermophilum
NCBI taxonomy Id: 759272
Other names: C. thermophilum var. thermophilum DSM 1495, Chaetomium thermophilum var. thermophilum DSM 1495
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