STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG16393.1PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: Isopropylmalate dehydrogenase; HAMAP: Isopropylmalate dehydrogenase; KEGG: drm:Dred_0288 3-isopropylmalate dehydrogenase. (361 aa)    
Predicted Functional Partners:
AEG16395.1
TIGRFAM: 3-isopropylmalate dehydratase, large subunit, prokaryotic; Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic; Homoaconitase/3-isopropylmalate dehydratase, large subunit, subgroup; HAMAP: Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic; KEGG: tjr:TherJR_0364 3-isopropylmalate dehydratase, large subunit; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha.
 0.999
AEG15252.1
TIGRFAM: Homoaconitase/3-isopropylmalate dehydratase, large subunit, subgroup; Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic; HAMAP: Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic; KEGG: pth:PTH_2519 3-isopropylmalate dehydratase large subunit; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha.
 0.998
AEG16394.1
PFAM: Aconitase A/isopropylmalate dehydratase small subunit, swivel; TIGRFAM: 3-isopropylmalate dehydratase, small subunit, bacterial-like; 3-isopropylmalate dehydratase, small subunit, subgroup; HAMAP: 3-isopropylmalate dehydratase small subunit; KEGG: pth:PTH_0533 3-isopropylmalate dehydratase small subunit.
 
 0.998
AEG16397.1
TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: sfu:Sfum_3023 acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Thiamine pyrophosphate enzyme, central region; Thiamine pyrophosphate enzyme, C-terminal TPP-binding.
 0.990
AEG16399.1
TIGRFAM: Acetolactate synthase, small subunit; KEGG: tjr:TherJR_0361 acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT.
  
 0.986
AEG15251.1
PFAM: Aconitase A/isopropylmalate dehydratase small subunit, swivel; TIGRFAM: 3-isopropylmalate dehydratase, small subunit, subgroup; HAMAP: 3-isopropylmalate dehydratase small subunit; KEGG: pth:PTH_2518 3-isopropylmalate dehydratase small subunit.
 
 0.984
AEG16400.1
TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: adg:Adeg_0223 acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Thiamine pyrophosphate enzyme, central region; Thiamine pyrophosphate enzyme, C-terminal TPP-binding.
 0.983
AEG14154.1
KEGG: pth:PTH_0736 acetolactate synthase 3 regulatory subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT.
  
 0.969
AEG16396.1
TIGRFAM: Bacterial 2-isopropylmalate synthase; KEGG: pth:PTH_0531 2-isopropylmalate synthase; PFAM: Pyruvate carboxyltransferase; 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain.
 
 0.959
AEG16401.1
PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; TIGRFAM: Dihydroxy-acid dehydratase; HAMAP: Dihydroxy-acid dehydratase; KEGG: pth:PTH_0526 dihydroxyacid dehydratase/phosphogluconate dehydratase.
 
  
 0.938
Your Current Organism:
Desulfofundulus kuznetsovii
NCBI taxonomy Id: 760568
Other names: D. kuznetsovii DSM 6115, Desulfofundulus kuznetsovii DSM 6115, Desulfotomaculum kuznetsovii 17, Desulfotomaculum kuznetsovii DSM 6115
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