node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aceA | fumA | ebA4473 | ebA173 | Isocitrate lyase. | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.422 |
aceA | glcB | ebA4473 | ebA819 | Isocitrate lyase. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.991 |
aceA | gltA | ebA4473 | ebA6687 | Isocitrate lyase. | Citrate synthase; Belongs to the citrate synthase family. | 0.491 |
aceA | maeB1 | ebA4473 | ebA4392 | Isocitrate lyase. | NADP-dependent malic enzyme. | 0.773 |
aceA | maeB2 | ebA4473 | ebA4043 | Isocitrate lyase. | NADP-dependent malic enzyme. | 0.773 |
aceA | pta | ebA4473 | ebA2247 | Isocitrate lyase. | Putative phosphate acetyltransferase (EC 2.3.1.8), gene: PTA OR RPA4567. | 0.709 |
acsA | acsA-2 | ebA1206 | ebA172 | Putative acetyl-coenzyme A synthetase. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.921 |
acsA | ebA4717 | ebA1206 | ebA4717 | Putative acetyl-coenzyme A synthetase. | Acyl-CoA synthetase. | 0.924 |
acsA | glcB | ebA1206 | ebA819 | Putative acetyl-coenzyme A synthetase. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.944 |
acsA | gltA | ebA1206 | ebA6687 | Putative acetyl-coenzyme A synthetase. | Citrate synthase; Belongs to the citrate synthase family. | 0.952 |
acsA | pta | ebA1206 | ebA2247 | Putative acetyl-coenzyme A synthetase. | Putative phosphate acetyltransferase (EC 2.3.1.8), gene: PTA OR RPA4567. | 0.934 |
acsA-2 | acsA | ebA172 | ebA1206 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Putative acetyl-coenzyme A synthetase. | 0.921 |
acsA-2 | ebA4717 | ebA172 | ebA4717 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Acyl-CoA synthetase. | 0.915 |
acsA-2 | fumA | ebA172 | ebA173 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.628 |
acsA-2 | glcB | ebA172 | ebA819 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.949 |
acsA-2 | gltA | ebA172 | ebA6687 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Citrate synthase; Belongs to the citrate synthase family. | 0.956 |
acsA-2 | pta | ebA172 | ebA2247 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Putative phosphate acetyltransferase (EC 2.3.1.8), gene: PTA OR RPA4567. | 0.936 |
ebA4717 | acsA | ebA4717 | ebA1206 | Acyl-CoA synthetase. | Putative acetyl-coenzyme A synthetase. | 0.924 |
ebA4717 | acsA-2 | ebA4717 | ebA172 | Acyl-CoA synthetase. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.915 |
ebA4717 | glcB | ebA4717 | ebA819 | Acyl-CoA synthetase. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.944 |