STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
alrAlanine racemase; COG: COG0787; Pfam: PF01168,PF00842; InterPro: IPR000821. (437 aa)    
Predicted Functional Partners:
ddl
D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
 
 
 0.987
ydiB
Hydrolase, P-loop family; Pfam: PF02367; InterPro: IPR003442.
  
 0.985
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
   
 0.928
ADP39662.1
Aminotransferase, class I/II; COG: COG0436; Pfam: PF00155; InterPro: IPR004839.
    
 0.814
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
 
   
 0.763
yeaZ
Universal bacterial protein YeaZ; Pfam: PF00814; InterPro: IPR000905.
     
 0.607
murD
UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
 
 
 0.599
rimI
Ribosomal-protein-alanine acetyltransferase; COG: COG0456; Pfam: PF00583; InterPro: IPR016181.
     
 0.588
penA
Penicillin-binding protein, transpeptidase domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR001460.
 
   
 0.563
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
 
    0.561
Your Current Organism:
Rothia dentocariosa
NCBI taxonomy Id: 762948
Other names: R. dentocariosa ATCC 17931, Rothia dentocariosa ATCC 17931, Rothia dentocariosa str. ATCC 17931, Rothia dentocariosa strain ATCC 17931
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.