STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV14566.1PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; KEGG: mlo:mll9685 ATP-dependent DNA ligase. (336 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.849
ku-2
Ku protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.808
ADV09177.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.807
ku
Ku protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.804
ADV13007.1
PFAM: ATP dependent DNA ligase; KEGG: mlo:mlr8107 hypothetical protein.
 
   
 0.787
ADV14138.1
PFAM: Protein of unknown function DUF2277; KEGG: mlo:msr7471 hypothetical protein.
  
     0.688
ADV11140.1
DNA topoisomerase; KEGG: mes:Meso_2773 hypothetical protein.
 
 
 
 0.593
ADV12910.1
TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: mlo:mll0423 DNA polymerase III subunit delta'.
   
 0.583
ADV14567.1
PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; thiamine pyrophosphate central domain-containing protein; KEGG: rlg:Rleg_5572 thiamine pyrophosphate protein domain protein TPP-binding; Belongs to the TPP enzyme family.
 
     0.582
ADV09248.1
Hypothetical protein; Manually curated; KEGG: mlo:mll5484 hypothetical protein.
 
 0.565
Your Current Organism:
Mesorhizobium ciceri biovar
NCBI taxonomy Id: 765698
Other names: M. ciceri biovar biserrulae WSM1271, Mesorhizobium ciceri biovar biserrulae WSM1271, Mesorhizobium ciceri biovar biserrulae str. WSM1271, Mesorhizobium ciceri biovar biserrulae strain WSM1271, Mesorhizobium ciceri bv. biserrulae WSM1271
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