STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFL75533.1PFAM: Toprim domain; DNA topoisomerase; TIGRFAM: DNA topoisomerase III, bacteria and conjugative plasmid. (860 aa)    
Predicted Functional Partners:
AFL74068.1
ATP-dependent DNA helicase RecQ; PFAM: Helicase conserved C-terminal domain; RQC domain; HRDC domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP-dependent DNA helicase, RecQ family.
 0.993
AFL76043.1
ERCC4-type nuclease.
  
 
 0.935
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.843
AFL75057.1
2-oxoacid:ferredoxin oxidoreductase, alpha subunit; PFAM: domain; 4Fe-4S binding domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
  
   0.841
AFL75655.1
Pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric.
  
   0.838
AFL75534.1
PFAM: Sel1 repeat.
 
 
   0.828
AFL76421.1
DNA repair exonuclease.
 
 
 0.792
rapA
DNA/RNA helicase, superfamily II, SNF2 family; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
  
 
 0.767
AFL73512.1
Hypothetical protein; Manually curated.
  
 0.763
AFL74414.1
TIGRFAM: DNA sulfur modification protein DndD.
  
 0.763
Your Current Organism:
Thiocystis violascens
NCBI taxonomy Id: 765911
Other names: T. violascens DSM 198, Thiocystis violascens DSM 198, Thiocystis violascens str. DSM 198, Thiocystis violascens strain DSM 198
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.