STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W4XRM6_STRPUAnamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...] (296 aa)    
Predicted Functional Partners:
W4Z611_STRPU
Uncharacterized protein.
    
 
 0.965
W4Y5N8_STRPU
FAD_binding_1 domain-containing protein.
    
 0.890
W4YZN5_STRPU
NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of the anamorsin/DRE2 homolog. Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family. In the N-terminal section; belongs to the flavodoxin family.
    
 0.890
W4Z883_STRPU
NAD_binding_1 domain-containing protein.
    
 0.890
W4XTW2_STRPU
Uncharacterized protein.
    
 
 0.835
W4YPL7_STRPU
Uncharacterized protein; Belongs to the BolA/IbaG family.
    
 
 0.819
W4XB56_STRPU
Fe_hyd_SSU domain-containing protein; Belongs to the NARF family.
   
 
 0.675
W4Y3W5_STRPU
Aminotran_5 domain-containing protein.
    
 
 0.647
W4XIL6_STRPU
Uncharacterized protein.
      
 0.638
W4YHK2_STRPU
Uncharacterized protein.
      
 0.638
Your Current Organism:
Strongylocentrotus purpuratus
NCBI taxonomy Id: 7668
Other names: S. purpuratus, purple sea urchin, purple urchin
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