STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W4YDD8_STRPUDynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (222 aa)    
Predicted Functional Partners:
W4Z3I8_STRPU
WD_REPEATS_REGION domain-containing protein.
   
 0.954
W4YQ82_STRPU
Uncharacterized protein.
  
 
 0.952
W4YRR7_STRPU
Uncharacterized protein.
   
 0.925
W4Z3Q6_STRPU
Uncharacterized protein.
    
 0.896
W4Y3K4_STRPU
Uncharacterized protein.
   
 0.894
W4YDV6_STRPU
CAP-Gly domain-containing protein.
   
 0.894
W4XRB8_STRPU
Uncharacterized protein.
    
 
 0.834
W4XRW9_STRPU
Uncharacterized protein.
   
 0.797
W4Z9T6_STRPU
F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
    
 0.769
W4XUR6_STRPU
FAM193_C domain-containing protein.
   
 0.766
Your Current Organism:
Strongylocentrotus purpuratus
NCBI taxonomy Id: 7668
Other names: S. purpuratus, purple sea urchin, purple urchin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.