STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W4YR50_STRPUUncharacterized protein. (112 aa)    
Predicted Functional Partners:
W4YLJ1_STRPU
Ubiquitin carboxyl-terminal hydrolase.
   
 0.989
W4XHL1_STRPU
USP domain-containing protein.
   
 0.988
W4XN86_STRPU
WD_REPEATS_REGION domain-containing protein.
    
 0.973
W4XMU0_STRPU
Ubiquitin-like domain-containing protein.
    
 0.896
W4XSR8_STRPU
Uncharacterized protein.
    
 0.893
W4YXX9_STRPU
FANCI_HD2 domain-containing protein.
    
 0.893
W4YHN1_STRPU
Ubiquitin-like domain-containing protein.
    
  0.888
UBIQP_STRPU
Polyubiquitin; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys [...]
    
 0.869
W4Z062_STRPU
Polyubiquitin Ubiquitin.
    
 0.869
W4XF90_STRPU
AAA domain-containing protein.
   
 0.832
Your Current Organism:
Strongylocentrotus purpuratus
NCBI taxonomy Id: 7668
Other names: S. purpuratus, purple sea urchin, purple urchin
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