node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEA20986.1 | AEA22228.1 | HMPREF9137_0783 | HMPREF9137_0785 | Hypothetical protein. | Putative UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.937 |
AEA20986.1 | alr | HMPREF9137_0783 | HMPREF9137_2283 | Hypothetical protein. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.849 |
AEA20986.1 | ddl | HMPREF9137_0783 | HMPREF9137_0399 | Hypothetical protein. | D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.713 |
AEA20986.1 | mraY | HMPREF9137_0783 | HMPREF9137_0789 | Hypothetical protein. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.620 |
AEA20986.1 | murD | HMPREF9137_0783 | HMPREF9137_0788 | Hypothetical protein. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.901 |
AEA20986.1 | murE | HMPREF9137_0783 | HMPREF9137_0790 | Hypothetical protein. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.736 |
AEA20986.1 | murF | HMPREF9137_0783 | HMPREF9137_0414 | Hypothetical protein. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.613 |
AEA20986.1 | murG | HMPREF9137_0783 | HMPREF9137_0786 | Hypothetical protein. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.948 |
AEA21098.1 | AEA22228.1 | HMPREF9137_0033 | HMPREF9137_0785 | Glycosyltransferase, group 4 family; Identified by match to protein family HMM PF00953. | Putative UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.498 |
AEA21098.1 | alr | HMPREF9137_0033 | HMPREF9137_2283 | Glycosyltransferase, group 4 family; Identified by match to protein family HMM PF00953. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.734 |
AEA21098.1 | murD | HMPREF9137_0033 | HMPREF9137_0788 | Glycosyltransferase, group 4 family; Identified by match to protein family HMM PF00953. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.611 |
AEA21098.1 | murE | HMPREF9137_0033 | HMPREF9137_0790 | Glycosyltransferase, group 4 family; Identified by match to protein family HMM PF00953. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.511 |
AEA21098.1 | murF | HMPREF9137_0033 | HMPREF9137_0414 | Glycosyltransferase, group 4 family; Identified by match to protein family HMM PF00953. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.547 |
AEA21098.1 | murG | HMPREF9137_0033 | HMPREF9137_0786 | Glycosyltransferase, group 4 family; Identified by match to protein family HMM PF00953. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.518 |
AEA21954.1 | alr | HMPREF9137_2449 | HMPREF9137_2283 | Homoserine dehydrogenase; Identified by match to protein family HMM PF00696; match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447; match to protein family HMM TIGR00657. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.757 |
AEA21954.1 | murD | HMPREF9137_2449 | HMPREF9137_0788 | Homoserine dehydrogenase; Identified by match to protein family HMM PF00696; match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447; match to protein family HMM TIGR00657. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.426 |
AEA21954.1 | murE | HMPREF9137_2449 | HMPREF9137_0790 | Homoserine dehydrogenase; Identified by match to protein family HMM PF00696; match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447; match to protein family HMM TIGR00657. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.406 |
AEA22228.1 | AEA20986.1 | HMPREF9137_0785 | HMPREF9137_0783 | Putative UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | Hypothetical protein. | 0.937 |
AEA22228.1 | AEA21098.1 | HMPREF9137_0785 | HMPREF9137_0033 | Putative UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | Glycosyltransferase, group 4 family; Identified by match to protein family HMM PF00953. | 0.498 |
AEA22228.1 | alr | HMPREF9137_0785 | HMPREF9137_2283 | Putative UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.754 |