STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fbpD-fructose 1,6-bisphosphatase; COGs: COG0158 Fructose-1 6-bisphosphatase; InterPro IPR020548: IPR000146; KEGG: ddf:DEFDS_1408 fructose-bisphosphatase; PFAM: Inositol phosphatase/fructose-16-bisphosphatase; SPTR: Fructose-1,6-bisphosphatase class 1; PFAM: Fructose-1-6-bisphosphatase. (333 aa)    
Predicted Functional Partners:
ADR18332.1
Transketolase domain-containing protein; COGs: COG0021 Transketolase; InterPro IPR005474: IPR005475: IPR005476; KEGG: ddf:DEFDS_0073 hypothetical protein; PFAM: Transketolase domain-containing protein; Transketolase central region; SPTR: Putative uncharacterized protein; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.
  
 
 0.960
ADR19835.1
COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771: IPR011289; KEGG: ddf:DEFDS_0062 fructose-bisphosphate aldolase class II; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Fructose-bisphosphate aldolase; SPTR: Fructose-bisphosphate aldolase, class II; TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist.
  
 
 0.939
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.929
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.924
pgi
COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR018189: IPR001672; KEGG: dap:Dacet_1293 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); SPTR: Glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase; Belongs to the GPI family.
   
 
 0.922
nfo
Apurinic endonuclease Apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
       0.825
ADR19291.1
KEGG: dap:Dacet_1701 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
ADR19294.1
COGs: COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains); InterPro IPR000189: IPR008258; KEGG: pmx:PERMA_1958 membrane-bound lytic murein transglycosylase C; PFAM: Lytic transglycosylase catalytic; SPTR: Membrane-bound lytic murein transglycosylase C; PFAM: Transglycosylase SLT domain; Domain of unknown function (DUF3393).
       0.705
ADR19295.1
KEGG: pmx:PERMA_1959 putative lipoprotein; SPTR: Putative lipoprotein.
       0.705
ADR19290.1
Diguanylate cyclase/phosphodiesterase; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR001633: IPR000160; KEGG: abu:Abu_1554 EAL/GGDEF domain-containing protein; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; SPTR: EAL/GGDEF domain protein; TIGRFAM: diguanylate cyclase; PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
  
    0.565
Your Current Organism:
Calditerrivibrio nitroreducens
NCBI taxonomy Id: 768670
Other names: C. nitroreducens DSM 19672, Calditerrivibrio nitroreducens DSM 19672, Calditerrivibrio nitroreducens Yu37-1, Calditerrivibrio nitroreducens str. DSM 19672, Calditerrivibrio nitroreducens strain DSM 19672, Deferribacteraceae bacterium Yu37-1
Server load: medium (52%) [HD]