• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
gdh protein (Thermoproteus tenax) - STRING interaction network
"gdh" - Glucose 1-dehydrogenase in Thermoproteus tenax
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gdhGlucose 1-dehydrogenase; Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. To a lesser extent, is also active with xylose as substrate, but mannose, arabinose, galactose, fructose 6-phosphate, glucose 6-phosphate, glycerinaldehyde 3-phosphate, ribose, sorbitol, ethanol, erythritol, or lactose are not oxidized by the enzyme. Can utilize both NAD(+) and NADP(+) as electron acceptor, with a marked preference for NADP(+). Is involved in the degradation of glucose through a non-phosphorylative variant of the Entner-Doudoroff pathway (347 aa)    
Predicted Functional Partners:
coxL/cutL
annotation not available (680 aa)
         
  0.835
coxM/cutM
annotation not available (278 aa)
         
  0.824
coxS/cutS
annotation not available (146 aa)
         
  0.820
plcC
annotation not available (510 aa)
   
        0.805
gad
annotation not available (391 aa)
 
 
  0.756
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate (308 aa)
   
 
  0.730
tpi
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family (226 aa)
 
 
 
  0.713
lysY/argC
Putative [LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily (351 aa)
 
     
  0.696
gabT
annotation not available (449 aa)
   
 
  0.682
icd
annotation not available (439 aa)
   
   
  0.661
Your Current Organism:
Thermoproteus tenax
NCBI taxonomy Id: 768679
Other names: T. tenax Kra 1, Thermoproteus tenax, Thermoproteus tenax DSM 2078, Thermoproteus tenax JCM 9277, Thermoproteus tenax Kra 1, Thermoproteus tenax str. Kra 1, Thermoproteus tenax strain Kra 1
Server load: low (8%) [HD]