STRINGSTRING
gdh protein (Thermoproteus tenax) - STRING interaction network
"gdh" - Glucose 1-dehydrogenase in Thermoproteus tenax
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gdhGlucose 1-dehydrogenase; Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. To a lesser extent, is also active with xylose as substrate, but mannose, arabinose, galactose, fructose 6-phosphate, glucose 6-phosphate, glycerinaldehyde 3-phosphate, ribose, sorbitol, ethanol, erythritol, or lactose are not oxidized by the enzyme. Can utilize both NAD(+) and NADP(+) as electron acceptor, with a marked preference for NADP(+). Is involved in the degradation of glucose through a non-phosphorylative variant of the Entner-Doudoroff pathway (347 aa)    
Predicted Functional Partners:
gapN
Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase, NAD(P) dependent (501 aa)
   
  0.946
coxL
Carbon monoxide dehydrogenase, large subunit (680 aa)
       
  0.927
putA
1-pyrroline-5-carboxylate dehydrogenase (522 aa)
   
  0.917
TTX_1101
Succinyl-CoA reductase (472 aa)
   
  0.917
TTX_0552
2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (298 aa)
   
  0.876
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP (510 aa)
       
  0.874
coxS
Carbon monoxide dehydrogenase, small subunit (146 aa)
       
    0.867
TTX_1867
Putative dehydrogenase (316 aa)
   
 
  0.861
TTX_1356
Hypothetical protein (108 aa)
   
 
  0.861
TTX_1106
Succinic semialdehyde reductase (363 aa)
 
 
0.828
Your Current Organism:
Thermoproteus tenax
NCBI taxonomy Id: 768679
Other names: T. tenax, T. tenax Kra 1, Thermoproteus tenax, Thermoproteus tenax DSM 2078, Thermoproteus tenax JCM 9277, Thermoproteus tenax Kra 1, Thermoproteus tenax str. Kra 1, Thermoproteus tenax strain Kra 1
Server load: low (7%) [HD]