• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
eif-1A protein (Thermoproteus tenax) - STRING interaction network
"eif-1A" - Translation initiation factor 1A in Thermoproteus tenax
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
eif-1ATranslation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (97 aa)    
Predicted Functional Partners:
rps13p
30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement (154 aa)
 
 
  0.999
rps11p
30S ribosomal protein S11; Located on the platform of the 30S subunit (140 aa)
 
 
  0.994
rps17p
30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5’-end of 16S ribosomal RNA (147 aa)
 
 
  0.993
rps7p
30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center (225 aa)
 
 
  0.991
rps9p
annotation not available (168 aa)
 
 
  0.989
rps5p
30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy (203 aa)
 
 
  0.986
rps15p
annotation not available (151 aa)
 
 
  0.980
rps12p
30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits (147 aa)
 
 
  0.978
rps4p
30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (172 aa)
 
 
  0.977
rps3p
30S ribosomal protein S3; Binds the lower part of the 30S subunit head (216 aa)
 
 
  0.976
Your Current Organism:
Thermoproteus tenax
NCBI taxonomy Id: 768679
Other names: T. tenax Kra 1, Thermoproteus tenax, Thermoproteus tenax DSM 2078, Thermoproteus tenax JCM 9277, Thermoproteus tenax Kra 1, Thermoproteus tenax str. Kra 1, Thermoproteus tenax strain Kra 1
Server load: low (14%) [HD]