STRINGSTRING
apbA protein (Thermoproteus tenax) - STRING interaction network
"apbA" - 2-dehydropantoate 2-reductase in Thermoproteus tenax
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
apbA2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (279 aa)    
Predicted Functional Partners:
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (265 aa)
     
  0.997
TTX_1080
Sugar kinase superfamily enzyme (285 aa)
       
    0.996
TTX_1081
Hypothetical protein (264 aa)
 
   
    0.945
thiI
Thiazole biosynthesis protein Thi I; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (472 aa)
   
   
  0.737
nixA
High-affinity nickel-transport protein (362 aa)
              0.612
pyrF
Orotidine-5’-phosphate decarboxylase (199 aa)
         
  0.556
pps
Phosphoenolpyruvate synthetase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (810 aa)
         
  0.547
gapN
Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase, NAD(P) dependent (501 aa)
   
   
  0.463
CoaE
Adenylate kinase (171 aa)
   
 
 
  0.440
ppdK
Pyruvate, phosphate dikinase (915 aa)
         
  0.411
Your Current Organism:
Thermoproteus tenax
NCBI taxonomy Id: 768679
Other names: T. tenax, T. tenax Kra 1, Thermoproteus tenax, Thermoproteus tenax DSM 2078, Thermoproteus tenax JCM 9277, Thermoproteus tenax Kra 1, Thermoproteus tenax str. Kra 1, Thermoproteus tenax strain Kra 1
Server load: low (7%) [HD]