Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
Automated, unsupervised textmining - searching for proteins that are frequently mentioned together.
Proteins whose genes are observed to be correlated in expression, across a large number of experiments.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
HEPN domain-containing protein (127 aa)
Predicted Functional Partners:
Minimal nucleotidyltrasferase family protein (101 aa)
Minimal nucleotidyltransferase family protein (109 aa)
Hypothetical protein (219 aa)
Putative nucleotidyltransferase (208 aa)
Minimal nucleotidyltrasferase family protein (124 aa)
GTPase SAR1-like protein (247 aa)
HEPN domain-containing protein (122 aa)
GDP-D-mannose dehydratase (167 aa)
RNA-binding protein, S1 and Zn-ribbon domains; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs (178 aa)
Your Current Organism:
NCBI taxonomy Id: 768679 Other names: T. tenax, T. tenax Kra 1, Thermoproteus tenax, Thermoproteus tenax DSM 2078, Thermoproteus tenax JCM 9277, Thermoproteus tenax Kra 1, Thermoproteus tenax str. Kra 1, Thermoproteus tenax strain Kra 1