STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. (308 aa)    
Predicted Functional Partners:
cis1,
Citrate synthase 1.
  
 0.989
cis2
Citrate synthase 2.
  
 0.989
fumC
Fumarate hydratase class II (fumarase).
  
 0.984
icd
Isocitrate dehydrogenase.
  
 
 0.983
fumB/ttdB
Fumarate hydratase class I, C-terminal domain / tartrate dehydratase beta subunit; Unknown EC_number=4.2.1.2 / 4.2.1.32.
  
 
 0.983
fumA/ttdA
Fumarate hydratase class I, N-terminal domain / tartrate dehydratase alpha subunit; Unknown EC_number=4.2.1.2 / 4.2.1.32.
  
 
 0.983
mae
Malate dehydrogenase (malic enzyme).
  
 0.966
gap
Glyceraldehyde-3-phosphate dehydrogenase (NADP-dependent).
  
 
 0.961
glcB
Malate synthase.
   
 0.951
aspC
Aspartate aminotransferase.
  
 0.939
Your Current Organism:
Thermoproteus tenax
NCBI taxonomy Id: 768679
Other names: T. tenax Kra 1, Thermoproteus tenax DSM 2078, Thermoproteus tenax JCM 9277, Thermoproteus tenax Kra 1, Thermoproteus tenax str. Kra 1, Thermoproteus tenax strain Kra 1
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